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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2017  >  35(4): 298-300,314

XIE Fahong, HUANG Zhi, ZHANG Haoyu, LI Dedong. Adverse reactions in hematological system induced by antibacterial agents[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 298-300,314. doi: 10.3969/j.issn.1006-0111.2017.04.003
Citation: XIE Fahong, HUANG Zhi, ZHANG Haoyu, LI Dedong. Adverse reactions in hematological system induced by antibacterial agents[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 298-300,314. doi: 10.3969/j.issn.1006-0111.2017.04.003
shu

Adverse reactions in hematological system induced by antibacterial agents

doi: 10.3969/j.issn.1006-0111.2017.04.003

  • Clinical Pharmacy Center, Department of Pharmacy, PLA General Hospital, Beijing 100853, China

  • Received Date: 2016-12-06
  • Rev Recd Date: 2017-05-03
  • In recent years, with the wide use of antimicrobial agents, the adverse reactions related to antimicrobial agents have attracted more and more attention.Among them, the adverse reactions in hematological system induced by antibacterial agents seriously affect patient's health and doctor's selection for antibiotics.For example, some beta lactam antibiotics can cause dysfunction of coagulation and hemolytic anemia.Chloramphenicol and sulfonamides can cause aplastic anemia.Linezolid can cause thrombocytopenia and anemia.It is important to understand the adverse reactions in hematological system caused by antibiotics.In this paper, the antibiotic induced adverse reactions in hematological system and their mechanism were summarized in order to provide information for the rational use of antimicrobial agents.
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    [3] Hanai Y, Matsuo K, Ogawa M, et al.A retrospective study of the risk factors for linezolid-induced thrombocytopenia and anemia[J].J Infect Chemother, 2016,22(8):536-542.
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    [11] Shearer MJ, Bechtold H, Andrassy K, et al.Mechanism of cephalosporin-induced hypoprothrombinemia: relation to cephalosporin side chain, vitamin K metabolism, and vitamin K status[J].J Clin Pharmacol, 1988,28(1):88-95.
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    [14] Garratty G.Drug-induced immune hemolytic anemia[J].Clin Adv Hematol Oncol, 2010,8(2): 98-101.
    [15] Kim S, Song KS, Kim HO, et al.Ceftriaxone induced immune hemolytic anemia: detection of drug-dependent antibody by ex-vivo antigen in urine[J].Yonsei Med J, 2002, 43(3):391-394.
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    [17] 云 璐, 王 帅, 李 杰.注射用拉氧头孢钠引起凝血障碍1例[J].中国现代应用药学, 2012,29(9):860-860.
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Adverse reactions in hematological system induced by antibacterial agents

doi: 10.3969/j.issn.1006-0111.2017.04.003
  • Clinical Pharmacy Center, Department of Pharmacy, PLA General Hospital, Beijing 100853, China
  • Received Date: 2016-12-06
  • Rev Recd Date: 2017-05-03

Abstract: In recent years, with the wide use of antimicrobial agents, the adverse reactions related to antimicrobial agents have attracted more and more attention.Among them, the adverse reactions in hematological system induced by antibacterial agents seriously affect patient's health and doctor's selection for antibiotics.For example, some beta lactam antibiotics can cause dysfunction of coagulation and hemolytic anemia.Chloramphenicol and sulfonamides can cause aplastic anemia.Linezolid can cause thrombocytopenia and anemia.It is important to understand the adverse reactions in hematological system caused by antibiotics.In this paper, the antibiotic induced adverse reactions in hematological system and their mechanism were summarized in order to provide information for the rational use of antimicrobial agents.

XIE Fahong, HUANG Zhi, ZHANG Haoyu, LI Dedong. Adverse reactions in hematological system induced by antibacterial agents[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 298-300,314. doi: 10.3969/j.issn.1006-0111.2017.04.003
Citation: XIE Fahong, HUANG Zhi, ZHANG Haoyu, LI Dedong. Adverse reactions in hematological system induced by antibacterial agents[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(4): 298-300,314. doi: 10.3969/j.issn.1006-0111.2017.04.003
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