CHEN Wenhui, SHEN Gang, CHEN Haisheng. High purity preparation and identification of three phthalide compounds from Apium graveolens[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 138-140. doi: 10.3969/j.issn.1006-0111.2017.02.010
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CHEN Wenhui, SHEN Gang, CHEN Haisheng. High purity preparation and identification of three phthalide compounds from Apium graveolens[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 138-140. doi: 10.3969/j.issn.1006-0111.2017.02.010
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High purity preparation and identification of three phthalide compounds from Apium graveolens
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Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
- Received Date: 2016-06-15
- Rev Recd Date:
2016-08-22
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Abstract
Objective Isolation, purification and structure identification of phthalides from Apium graveolens L. Methods Silica gel column and preparative TLC chromatography were used to isolate and purify the phthalide compounds. The structures of those compounds were determined through spectral analysis. Results Three pure compounds were identified as 3-n-butylphthalide, sedanenolide and sedanolide. Conclusion Three pure phthalide compounds can be used as analytical reference standard for quantitative analysis of A. graveolens.
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