Research and establishment of antibiotics differentiated indexes in clinical application of cardiothoracic surgery in our hospital

Key words: 
• anti-bacterial drug /
• the clinical application specification /
• differentiation index /
• chest depart

Abstract: Objective To formulate the clinical application specification of antibiotics, make a deference index of antibacterial drugs in chest department according to the investigation about the antibiotics' utility situation in chest department in 2014 and provide a theoretic foundation for the clinical doctor to promote the clinical rational drug use. Methods The antibiotics' application information of 300 cases inpatients in the chest department of a hospital in 2014 were researched and analyzed through retrospection, regarding with the relevant regulations and related clinical practice guidelines, the clinical application specification of antibiotics was formulated and the analysis,calculation, statistics to the actual and theoretical value of the rate and intensity of antibiotics' application, the application rate of the prophylactic antibiotics of type I incision on the inpatients in the chest department had been done. The differentiation index of them were establish. Results The rates of the actual antibiotics' application and the prophylactic antibiotics of type I incision respectively were 72.7% and 92.6%, while the intensity of antibiotics' application was 61.2 DDDs/(100 persons·d). The deference indexes of them were developed 69.3%, 63.0% and 49.3 DDDs/(100 persons·d). Conclusions There're still much irrational places in the use of antibiotics in chest department of the hospital. It's essential to strengthen supervision in order to promote the rational use of antibiotics in clinical practice.