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Volume 34 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2016  >  34(2): 188-190,192

MA Zongqiang, AN Hongliang. Application analysis of antihypertensive drugs in outpatient[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(2): 188-190,192. doi: 10.3969/j.issn.1006-0111.2016.02.024
Citation: MA Zongqiang, AN Hongliang. Application analysis of antihypertensive drugs in outpatient[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(2): 188-190,192. doi: 10.3969/j.issn.1006-0111.2016.02.024
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Application analysis of antihypertensive drugs in outpatient

doi: 10.3969/j.issn.1006-0111.2016.02.024

  • Shanghai Meishan Hospital, Nanjing 210039, China

  • Received Date: 2015-08-24
  • Rev Recd Date: 2016-01-18
  • Objective To study the application of outpatient oral antihypertensive drugs in Shanghai Meishan Hospital, and provide a guide for clinical rational drug use. Methods The utilization of antihypertensive drugs in outpatients of our hospital was analyzed statistically by using defined daily dose(DDD) recommended by WHO. Results 1 The most commonly used antihypertensive drugs in outpatients was calcium antagonist(51.98%), followed by angiotensin receptor blockers(16.60%), fixed-dose combination(13.23%), β-blockers(11.93%), diuretics(3.67%), angiotensin-converting enzyme inhibitors(2.40%), and α,β-blockers(0.19%). 2 The combination therapy was fewer in outpatients than monotherapy(32.99% versus 67.01%). Conclusion The application of antihypertensive drugs is basically reasonable in outpatient of our hospital, but the combination therapy was inadequate.
  • [1] 林凡礼,战义强,贾贡献,等.中国门诊高血压患者血压达标现状及影响因素分析[J].中华高血压杂志,2013,21(2):170-174.
    [2] 中国高血压防治指南修订委员会.中国高血压防治指南2010[J].中华心血管杂志,2011,39(7):579-616.
    [3] James PA,Oparil S,Carter BL,et al.2014 evidence-based guideline for the management of high blood pressure in adults:report from the panel members appointed to the Eighth Joint National Committee(JNC8)[J].JAMA,2014,311(5):507-520.
    [4] Lindholm LH,Carlberg B,Samuelsson O.Should beta blockers remain first choice in the treatment of primary hypertension? A meta-analysis[J].Lancet,2005,366(9496):1545-1553.
    [5] Bradley HA,Wiysonge CS,Volmink JA,et al.How strong is the evidence for use of beta blockers as first-line therapy for hypertension? Systematic review and meta-analysis[J].J Hypertens,2006,24,(11):2131-2141.
    [6] Ma W,Zhang Y.Low rate of resistant hypertension in Chinese patients with hypertension:an analysis of the HOT-CHINA study[J].J Hypertens,2013,31(12):2386-2390.
    [7] 廖梅,陈玲.琥珀酸美托洛尔缓释片对高血压患者血压变异性的影响[J].国际医药卫生导报,2012,18(11):1618.
    [8] 胡大一,刘力生,余金明,等.中国门诊高血压患者治疗现状登记研究[J].中华心血管病杂志,2010,38(3):230-238.
    [9] Brenner R,Waeber B,Allemann Y.Medical treatment of hypertension in Switzerland.The 2009 Swiss Hypertension Survey(SWISSHYPE)[J].Swiss Med Wkly,2011,141(w13169):1-7.
    [10] Clement YN,Ali S,Harripaulsingh S,et al.Drug prescribing for hypertension at primary healthcare facilities in Trinidad[J].West Indian Med J,2012,61(1):43-48.
    [11] 秦际芳.氯沙坦钾氢氯噻嗪片治疗老年原发性高血压疗效观察[J].慢性病学杂志,2014,15(3):220-221.
    [12] 潘华兴,宁观林,林宇彪.氯沙坦钾氢氯噻嗪片治疗老年原发性高血压的研究[J].齐齐哈尔医学院学报,2014,35(8):1128-1129.
    [13] 袁静平.缬沙坦/氢氯噻嗪治疗轻中度原发性高血压患者疗效和安全性[J].中国医药导刊,2014,16(2):280-281.
    [14] 姜忠梅,李红霞,卢冬喜.氯沙坦钾氢氯噻嗪片治疗高血压合并2型糖尿病的临床研究[J].中国临床医生,2014,42(5):56-57.
    [15] 肖玉光,邓伟峰.非洛地平、缬沙坦分别联合氢氯噻嗪治疗老年ISH的疗效及安全性研究[J].重庆医学,2014,43(6):725-728.
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Application analysis of antihypertensive drugs in outpatient

doi: 10.3969/j.issn.1006-0111.2016.02.024
  • Shanghai Meishan Hospital, Nanjing 210039, China
  • Received Date: 2015-08-24
  • Rev Recd Date: 2016-01-18

Abstract: Objective To study the application of outpatient oral antihypertensive drugs in Shanghai Meishan Hospital, and provide a guide for clinical rational drug use. Methods The utilization of antihypertensive drugs in outpatients of our hospital was analyzed statistically by using defined daily dose(DDD) recommended by WHO. Results 1 The most commonly used antihypertensive drugs in outpatients was calcium antagonist(51.98%), followed by angiotensin receptor blockers(16.60%), fixed-dose combination(13.23%), β-blockers(11.93%), diuretics(3.67%), angiotensin-converting enzyme inhibitors(2.40%), and α,β-blockers(0.19%). 2 The combination therapy was fewer in outpatients than monotherapy(32.99% versus 67.01%). Conclusion The application of antihypertensive drugs is basically reasonable in outpatient of our hospital, but the combination therapy was inadequate.

MA Zongqiang, AN Hongliang. Application analysis of antihypertensive drugs in outpatient[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(2): 188-190,192. doi: 10.3969/j.issn.1006-0111.2016.02.024
Citation: MA Zongqiang, AN Hongliang. Application analysis of antihypertensive drugs in outpatient[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(2): 188-190,192. doi: 10.3969/j.issn.1006-0111.2016.02.024
shu

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