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PANG Suqiu, JIN Xiaoqin, SUN Aijing, WANG Guoquan, XU Rui'an. Constituent analysis, analgesic and anti-inflammatory activities of leaves essential oil of Schefflera octophylla[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 56-58,78. doi: 10.3969/j.issn.1006-0111.2016.01.015
Citation: PANG Suqiu, JIN Xiaoqin, SUN Aijing, WANG Guoquan, XU Rui'an. Constituent analysis, analgesic and anti-inflammatory activities of leaves essential oil of Schefflera octophylla[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 56-58,78. doi: 10.3969/j.issn.1006-0111.2016.01.015

Constituent analysis, analgesic and anti-inflammatory activities of leaves essential oil of Schefflera octophylla

doi: 10.3969/j.issn.1006-0111.2016.01.015
  • Received Date: 2015-01-14
  • Rev Recd Date: 2015-06-16
  • Objective To investigate the constituents and analgesic and anti-inflammatory effects of leaves essential oil in Schefflera octophylla. Methods SOLEO was dilated by water vapor. The mouse acetic acid-induced twisting test and mouse auricle swelling test induced by xylene were employed to evaluate the anti-inflammation and analgesia effects of SOLEO. Results 55 constituents of SOLEO were identified by GC-MS. The major constituents, 4-terpenol, (-)-spthulenol,caryophllene oxide and β-linalool with total percent of 51.86% were found. The twisting number and relieve swollen auricle of mice induced by xylene were significantly reduced by SOLEO. Conclusion SOLEO was the major active components of anti-inflammation and analgesia.
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    [6] 吴春丽,李杰明,杭 晔,等. GC法测定鱼腥草注射液中(-)-4-萜品醇的含量[J].中国药房,2013,24(44):4204-4206.
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    [9] Huo M,Cui X,Xue J,et al.Anti-inflammatory effects of linalool in RAW 264.7 macrophages and lipopolysaccharide-induced lung injury model[J].J Surg Res,2013,180(1): 47-52.
    [10] Batista PA,Werner MF,Oliveira EC,et al. Evidence for the involvement of ionotropic glutamatergic receptors on the antinociceptive effect of (-) -linalool in mice[J].Neurosci Lett,2008,440(3): 299-304.
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Constituent analysis, analgesic and anti-inflammatory activities of leaves essential oil of Schefflera octophylla

doi: 10.3969/j.issn.1006-0111.2016.01.015

Abstract: Objective To investigate the constituents and analgesic and anti-inflammatory effects of leaves essential oil in Schefflera octophylla. Methods SOLEO was dilated by water vapor. The mouse acetic acid-induced twisting test and mouse auricle swelling test induced by xylene were employed to evaluate the anti-inflammation and analgesia effects of SOLEO. Results 55 constituents of SOLEO were identified by GC-MS. The major constituents, 4-terpenol, (-)-spthulenol,caryophllene oxide and β-linalool with total percent of 51.86% were found. The twisting number and relieve swollen auricle of mice induced by xylene were significantly reduced by SOLEO. Conclusion SOLEO was the major active components of anti-inflammation and analgesia.

PANG Suqiu, JIN Xiaoqin, SUN Aijing, WANG Guoquan, XU Rui'an. Constituent analysis, analgesic and anti-inflammatory activities of leaves essential oil of Schefflera octophylla[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 56-58,78. doi: 10.3969/j.issn.1006-0111.2016.01.015
Citation: PANG Suqiu, JIN Xiaoqin, SUN Aijing, WANG Guoquan, XU Rui'an. Constituent analysis, analgesic and anti-inflammatory activities of leaves essential oil of Schefflera octophylla[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 56-58,78. doi: 10.3969/j.issn.1006-0111.2016.01.015
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