Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 33 Issue 4
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2015  >  33(4): 363-365

YANG Xijng, ZHOU Fuping, ZHANG Qian, QIAN Qijun. Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 363-365. doi: 10.3969/j.issn.1006-0111.2015.04.019
Citation: YANG Xijng, ZHOU Fuping, ZHANG Qian, QIAN Qijun. Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 363-365. doi: 10.3969/j.issn.1006-0111.2015.04.019
shu

Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome

doi: 10.3969/j.issn.1006-0111.2015.04.019

  • Department of Bio-therapy, Eastern Hepatobiliary Surgical Hospital affliated to Second Military Medical University, Shanghai 200438, China

  • Received Date: 2015-02-11
  • Rev Recd Date: 2015-05-14
  • Objective To investigate the clinical features and treatment of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma (SPTCL) associated hemophagocytic syndrome (HPS). Methods A retrospective analysis of case clinical data with liver cirrhosis complicated by SPTCL associated HPS was done in August 2014 in our hospital. Results Because of different phenotypes of T cell receptor (TCR), the aggression, treatment response and prognosis of the disease were significantly different. The patients with HPS had poor treatment effect and short survival period. Conclusion Liver cirrhosis with hepatitis B complicated by SPTCL associated HPS is rare, Bone marrow morphology, pathology, immunohistochemistry and gene rearrangement detection as soon as possible are important for early diagnosis.To control HBV early and effectively is particularly important. Early diagnosis and treatment are important to prolong survival.
  • [1] Gonzalez CL, Medeiros LJ, Braziel RM, et al.T-cell lymphoma involving subcutaneous tissue A clinicopathologic entity commonly associated with hemophagocytic syndrome[J]. Am J Surg Pathol,l991,15:17-27.
    [2] Go RS, Wester SM.Immunophenotypic and molecular features, clinical outcomes, treatments and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature[J].Cancer, 2004,l01(6):1404-1413.
    [3] Takeshita M,Okamura S,Oshiro Y, et al.Clinicopathologic differences between 22 cases of CD56-negative and CD56-positive subcutaneous panniculitis-like lymphoma in Japan[J].Hum Pathol,2004,35(2):231-239.
    [4] 马 兰,柴俊月,郑雯琦,等继发于淋巴瘤的嗜血细胞综合征6例临床分析[J].世界最新医学信息文摘,2014,14(2):96.
    [5] Huang JJ, Cai MY, Ye S,et al. Clinical analysis of 19 cases of subcutaneous panniculitis T-cell lymphoma with literature review[J]. Ai Zheng,2009,28 (10): 1093-1099.
    [6] Briki H,Bouaziz J D,Molinier-Frenkel V, et al.Subcutaneous panniculitis-like T-cell lymphoma αβ:complete sustained remission with corticosteroids and methotrexate[J].Br J Dermatol, 2010,163(5):1136-1138.
    [7] Guenova E, Schanz S, Hoetzenecker W, et al. Systemic corticosteroids for subcutaneous panniculitis-like T-cell lymphoma[J]. Br J Dermatol,2014,171 (4): 891-894.
    [8] Sakurai E, Satoh T, Akiko YA, et al. Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) with hemophagocytosis (HPS): successful treatment using high-dose chemotherapy (BFM-NHL & ALL-90) and autologous peripheral blood stem cell transplantation[J]. J Clin Exp Hematop, 2013,53 (2): 135-140.
    [9] Chen R, Liu L,Liang YM,et al. Treatment relapsed subcutaneous panniculitis-like T-cell lymphoma together HPS by cyclosporin A[J]. Hematol Rep,2010,2 (1): e9.
    [10] Zhang X,Schlaak M,Fabri M, et al.Successful treatment of a panniculitis-like primary cutaneous T-Cell lymphoma of the α/β type with bexarotene[J].Case Rep Dennatol,2012,4(1):56-60.
    [11] Bashey S,Krathen M,Abdulla F, et al.Romidepsin is effective in subcutaneous panniculitis-like T-cell lymphoma[J].J Clin Oncol, 2012,30(24):e221-225.
    [12] Nagai K, Nakano N, Iwai T, et al. Pediatric subcutaneous panniculitis-like T-cell lymphoma with favorable result by immunosuppressive therapy: a report of two cases[J]. Pediatr Hematol Oncol,2014,31 (6): 528-533.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(3230) PDF downloads(617) Cited by()

Related
Proportional views

Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome

doi: 10.3969/j.issn.1006-0111.2015.04.019
  • Department of Bio-therapy, Eastern Hepatobiliary Surgical Hospital affliated to Second Military Medical University, Shanghai 200438, China
  • Received Date: 2015-02-11
  • Rev Recd Date: 2015-05-14

Abstract: Objective To investigate the clinical features and treatment of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma (SPTCL) associated hemophagocytic syndrome (HPS). Methods A retrospective analysis of case clinical data with liver cirrhosis complicated by SPTCL associated HPS was done in August 2014 in our hospital. Results Because of different phenotypes of T cell receptor (TCR), the aggression, treatment response and prognosis of the disease were significantly different. The patients with HPS had poor treatment effect and short survival period. Conclusion Liver cirrhosis with hepatitis B complicated by SPTCL associated HPS is rare, Bone marrow morphology, pathology, immunohistochemistry and gene rearrangement detection as soon as possible are important for early diagnosis.To control HBV early and effectively is particularly important. Early diagnosis and treatment are important to prolong survival.

YANG Xijng, ZHOU Fuping, ZHANG Qian, QIAN Qijun. Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 363-365. doi: 10.3969/j.issn.1006-0111.2015.04.019
Citation: YANG Xijng, ZHOU Fuping, ZHANG Qian, QIAN Qijun. Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 363-365. doi: 10.3969/j.issn.1006-0111.2015.04.019
shu

    HTML

Reference (12)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return