XU Nongzhang, JIN Zhonghua, WANG Zhijing. Study on drug resistance of Acinetobacter baumannii before and after special anti-bacterial drugs remediation[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(3): 203-205. doi: 10.3969/j.issn.1006-0111.2014.03.010
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XU Nongzhang, JIN Zhonghua, WANG Zhijing. Study on drug resistance of Acinetobacter baumannii before and after special anti-bacterial drugs remediation[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(3): 203-205. doi: 10.3969/j.issn.1006-0111.2014.03.010
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Study on drug resistance of Acinetobacter baumannii before and after special anti-bacterial drugs remediation
- Received Date: 2013-03-13
- Rev Recd Date:
2013-11-11
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Abstract
Objective To investigate the drug resistance of Acinetobacter baumannii and antibiotics use density of all kinds of antibacterial drugs before and after special antibacterial drugs remediation, provide evidence for the follow-up intervention strategies. Methods The experimental results of detected 562 cases Acinetobacter baumannii and sensitivity test were analyzed in our hospital in 2011-2012, combined with using of every type of antibacterial drugs on different time period. Results The number of bacteria detected half year had no significant difference during 2011-2012. The antibiotics use density of beta-lactam、fluroquinoloncs and aminoglycosides declined 22.22(31.92%)、4.19(46.29%)、5.24(68.83%) respectively by special antibacterial drugs remediation. Beta-lactam resistance rates declined significantly to 25%~30%, fluroquinoloncs and aminoglycosides resistance rates also declined, from 50% of the critical point to 20%~30% in the second half of 2012. Conclusion Standardization of antibiotics use density of various antibacterial drugs could help reduce bacterial resistance.
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