Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 32 Issue 2
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2014  >  32(2): 121-123

ZHANG Liping. Determination of gardenoside and paeoniflorin in Ankun granule by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 121-123. doi: 10.3969/j.issn.1006-0111.2014.02.012
Citation: ZHANG Liping. Determination of gardenoside and paeoniflorin in Ankun granule by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 121-123. doi: 10.3969/j.issn.1006-0111.2014.02.012
shu

Determination of gardenoside and paeoniflorin in Ankun granule by HPLC

doi: 10.3969/j.issn.1006-0111.2014.02.012

  • Wenzhou Institute for Drug Control, Wenzhou 325028, China

  • Received Date: 2013-09-05
  • Rev Recd Date: 2013-11-07
  • Objective To establish the HPLC method for the determination of gardenoside and paeoniflorin in Ankun granule. Methods The column was Agilent Eclipse XDB C18 (250 mm×4.6 mm,5 μm),and the acetonitrile-water(14:86) was used as the mobile phase.The detective wavelength was set at 230 nm. Results For the gardenoside,the linear range was 0.0715 2-0.357 6 μg,r=0.999 8 and the average recovery was 98.22% with RSD of 1.25%.For the Paeoniflorin,the linear range was 0.071 97-0.359 85 μg,r=0.999 2 and the average recovery was 98.40% with RSD of 0.68%. Conclusion The method was simple,reliable,and accurate which could be applied to the quality control of the drug.
  • [1] 中华人民共和国卫生部药典委员会.卫生部药品标准中药成方制剂:第十九册[S].1998:72.
    [2] 吴 毅,张文惠,王永刚.HPLC法测定安坤颗粒中芍药苷的含量[J].江西中医学院学报,2002,14(1):42.
    [3] 汤 浩,封士兰,闵光涛,等. HPLC同时测定赤栀黄胶囊中栀子苷和芍药苷的含量[J].中成药,2004,26(5):361-364.
    [4] 李卫华.HPLC法测定丹栀逍遥丸中芍药苷的含量[J].海峡药学,2001,13(2):38.
    [5] 刘阿静,齐广才,刘珍叶,等. RP-HPLC法测定防风通圣丸中芍药苷、栀子苷、黄芩苷和连翘苷的含量[J].西北药学杂志,2012,27(5):415-417.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2351) PDF downloads(87) Cited by()

Related
Proportional views

Determination of gardenoside and paeoniflorin in Ankun granule by HPLC

doi: 10.3969/j.issn.1006-0111.2014.02.012
  • Wenzhou Institute for Drug Control, Wenzhou 325028, China
  • Received Date: 2013-09-05
  • Rev Recd Date: 2013-11-07

Abstract: Objective To establish the HPLC method for the determination of gardenoside and paeoniflorin in Ankun granule. Methods The column was Agilent Eclipse XDB C18 (250 mm×4.6 mm,5 μm),and the acetonitrile-water(14:86) was used as the mobile phase.The detective wavelength was set at 230 nm. Results For the gardenoside,the linear range was 0.0715 2-0.357 6 μg,r=0.999 8 and the average recovery was 98.22% with RSD of 1.25%.For the Paeoniflorin,the linear range was 0.071 97-0.359 85 μg,r=0.999 2 and the average recovery was 98.40% with RSD of 0.68%. Conclusion The method was simple,reliable,and accurate which could be applied to the quality control of the drug.

ZHANG Liping. Determination of gardenoside and paeoniflorin in Ankun granule by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 121-123. doi: 10.3969/j.issn.1006-0111.2014.02.012
Citation: ZHANG Liping. Determination of gardenoside and paeoniflorin in Ankun granule by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 121-123. doi: 10.3969/j.issn.1006-0111.2014.02.012
shu

    HTML

Reference (5)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return