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YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
Citation: YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005

Role of apoptosis in radiation-induced tissue damage

doi: 10.3969/j.issn.1006-0111.2014.02.005
  • Received Date: 2013-03-11
  • Rev Recd Date: 2013-06-14
  • Ionizing radiation is able to induce tissue damage, which is related to cell apoptosis, necrosis and inflammation, etc. The signaling pathway underlying radiation-induced apoptosis remains unclear. However, it's well-accepted that several targets were activated in this process, such as poly (ADP-ribose) polymerase, p53, p38, ceramide, free radicals, etc. Based on these targets, the role of apoptosis in radiation-induced tissue damage was elaborated in this review briefly.
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Role of apoptosis in radiation-induced tissue damage

doi: 10.3969/j.issn.1006-0111.2014.02.005

Abstract: Ionizing radiation is able to induce tissue damage, which is related to cell apoptosis, necrosis and inflammation, etc. The signaling pathway underlying radiation-induced apoptosis remains unclear. However, it's well-accepted that several targets were activated in this process, such as poly (ADP-ribose) polymerase, p53, p38, ceramide, free radicals, etc. Based on these targets, the role of apoptosis in radiation-induced tissue damage was elaborated in this review briefly.

YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
Citation: YANG Hong, NI Min, ZHAO Xinbin, TAO Xia. Role of apoptosis in radiation-induced tissue damage[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 96-97,149. doi: 10.3969/j.issn.1006-0111.2014.02.005
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