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LI Yu-qing. Cost-effectiveness analysis of three kinds of drugs for osteoporosis[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 143-144,150. doi: 10.3969/j.issn.1006-0111.2013.02.018
Citation: LI Yu-qing. Cost-effectiveness analysis of three kinds of drugs for osteoporosis[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 143-144,150. doi: 10.3969/j.issn.1006-0111.2013.02.018

Cost-effectiveness analysis of three kinds of drugs for osteoporosis

doi: 10.3969/j.issn.1006-0111.2013.02.018
  • Received Date: 2012-05-03
  • Rev Recd Date: 2012-10-29
  • Objective To investigate economic effects of three kinds of drugs in treatment of osteoporosis. Methods 135 cases were divided into three groups, A group with alendronate sodium and vitamin D3 tablets 70 mg/2 800 IU, once a week, early morning,B group with salmon calcitonin nasal spray, once a day every time 100 IU, C group with zoledronicacid injection 4 mg, once a year. All groups were treated for one year, three groups of patients were added calcium at the same time. Efficacy was observed. Cost-effectiveness analysis was used. Results In the improvement of bone pain, A group was 66.67%, B group was 55.56%, C group was 80%. C group was higher than those in group A, group B, group efficacy was statistically significant in three groups(P<0.05); The effectiveness ratio of A group, B group, C group was 59.52,43.61,46.70 respectively. B group was superior to A group and C group in the terms of economic, but group B had the lowest efficacy in all groups. Conclusion C group was the optimal solution for osteoporosis.
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    [2] Bonnick SL. Osteoporosis in men and women[J]. Clin Cornerston,2006,8(1):28
    [3] 陈 洁.药物经济学[M].第3版.成都:成都科技大学出版社,2000:97.
    [4] 艾伟朋,方红成.三种他汀类药物治疗高脂血症的经济学分析[J]. 现代医药卫生,2005, 21(10):1200.
    [5] 孔晓东. 药物经济学:概念、方法和应用[J].国外医学药学分册,1994,21(1):16.
    [6] 蒋凤艳.原发性骨质疏松症的发病机制和预防[J].广西医科大学学报,2004,21(3):437.
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Cost-effectiveness analysis of three kinds of drugs for osteoporosis

doi: 10.3969/j.issn.1006-0111.2013.02.018

Abstract: Objective To investigate economic effects of three kinds of drugs in treatment of osteoporosis. Methods 135 cases were divided into three groups, A group with alendronate sodium and vitamin D3 tablets 70 mg/2 800 IU, once a week, early morning,B group with salmon calcitonin nasal spray, once a day every time 100 IU, C group with zoledronicacid injection 4 mg, once a year. All groups were treated for one year, three groups of patients were added calcium at the same time. Efficacy was observed. Cost-effectiveness analysis was used. Results In the improvement of bone pain, A group was 66.67%, B group was 55.56%, C group was 80%. C group was higher than those in group A, group B, group efficacy was statistically significant in three groups(P<0.05); The effectiveness ratio of A group, B group, C group was 59.52,43.61,46.70 respectively. B group was superior to A group and C group in the terms of economic, but group B had the lowest efficacy in all groups. Conclusion C group was the optimal solution for osteoporosis.

LI Yu-qing. Cost-effectiveness analysis of three kinds of drugs for osteoporosis[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 143-144,150. doi: 10.3969/j.issn.1006-0111.2013.02.018
Citation: LI Yu-qing. Cost-effectiveness analysis of three kinds of drugs for osteoporosis[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 143-144,150. doi: 10.3969/j.issn.1006-0111.2013.02.018
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