Application of microbial transformation in natural products research

LIU Qing-xin; LI Hui-liang; LIU Run-hui

doi:10.3969/j.issn.1006-0111.2012.05.001

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With the continuous development of biotechnology technology, microbial transformation gradually was applied to the study of natural products. The specific effective reactions, mild reaction conditions and high yield of the microbial transformation were outlined in this paper. The applications were reviewed in the microbial transformation of natural products in recent five years, especially in anthraquinones, flavonoids, terpenoids, steroids, alkaloids and glycosides. The developments of microbial transformation were prospected.

Application of microbial transformation in natural products research

1. Department of Pharmacy, Fujian Traditional Chinese Medicine University, Fuzhou 350108, China

2. Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

Received Date: 2012-02-02

Rev Recd Date: 2012-03-26

Key words:

Abstract: With the continuous development of biotechnology technology, microbial transformation gradually was applied to the study of natural products. The specific effective reactions, mild reaction conditions and high yield of the microbial transformation were outlined in this paper. The applications were reviewed in the microbial transformation of natural products in recent five years, especially in anthraquinones, flavonoids, terpenoids, steroids, alkaloids and glycosides. The developments of microbial transformation were prospected.

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Application of microbial transformation in natural products research

doi: 10.3969/j.issn.1006-0111.2012.05.001

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