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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(3): 213-215

CHEN Yi, PU Jian-ying. Therapeutic effect of Tiotropium bromide on moderate to severe chronic obstructive pulmonary disease[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(3): 213-215. doi: 10.3969/j.issn.1006-0111.2012.03.015
Citation: CHEN Yi, PU Jian-ying. Therapeutic effect of Tiotropium bromide on moderate to severe chronic obstructive pulmonary disease[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(3): 213-215. doi: 10.3969/j.issn.1006-0111.2012.03.015
shu

Therapeutic effect of Tiotropium bromide on moderate to severe chronic obstructive pulmonary disease

doi: 10.3969/j.issn.1006-0111.2012.03.015

  • Department of Respiratory , Shanghai Gonghui Hospital,Shanghai 200041,China

  • Received Date: 2012-03-28
  • Rev Recd Date: 2012-04-18
  • Objective To investigate the effectiveness and safety of the inhalation of tiotropium bromide in the treatment of moderate to severe chronic obstructive pulmonary disease. Methods 35 cases with chronic obstructive pulmonary disease during 2010 June to 2011 November in our department were observed which was used by tiotropium bromide dry powder (Spirva, 18 μg, once daily) . The pulmonary function, average daily use of beta agonists times and cardiopulmonary insufficiency in patients with Plasma brain natriuretic peptide levels(BNP)were compared before treatment and three months after the treatment. The number of admissions three months before treatment and three months after treatment was recorded,and the adverse reaction observed. Results Tiotropium pulmonary function was improved significantly, the number of daily use of beta agonists reduced, peripheral blood BNP decreased obviously, the number of acute exacerbation of seizures became less,no serious adverse reaction occurred. Conclusion Tiotropium bromide was effectiveness and safety in moderate to severe chronic obstructive pulmonary disease.
  • [1] 闫 莉,吕妍琨.国产噻托溴铵对稳定期慢性阻塞性肺疾病患者的影响[J].中国新药杂志,2010,19(2):127.
    [2] 杜昆钰,戴路明.噻托溴铵在慢性阻塞性肺疾病治疗中的研究进展[J].中外医疗,2009, 15(11):179.
    [3] Iwanaga Y,Nishi I,Furuichi S,et al. B-type nalriuretic peptide strongly reflects diastolic wall stress in patients with chronic heart failure:comparison between systolic and diastolic heart failure[J].Jam Coll Cardiol,2006,47(4):742.
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Therapeutic effect of Tiotropium bromide on moderate to severe chronic obstructive pulmonary disease

doi: 10.3969/j.issn.1006-0111.2012.03.015
  • Department of Respiratory , Shanghai Gonghui Hospital,Shanghai 200041,China
  • Received Date: 2012-03-28
  • Rev Recd Date: 2012-04-18

Abstract: Objective To investigate the effectiveness and safety of the inhalation of tiotropium bromide in the treatment of moderate to severe chronic obstructive pulmonary disease. Methods 35 cases with chronic obstructive pulmonary disease during 2010 June to 2011 November in our department were observed which was used by tiotropium bromide dry powder (Spirva, 18 μg, once daily) . The pulmonary function, average daily use of beta agonists times and cardiopulmonary insufficiency in patients with Plasma brain natriuretic peptide levels(BNP)were compared before treatment and three months after the treatment. The number of admissions three months before treatment and three months after treatment was recorded,and the adverse reaction observed. Results Tiotropium pulmonary function was improved significantly, the number of daily use of beta agonists reduced, peripheral blood BNP decreased obviously, the number of acute exacerbation of seizures became less,no serious adverse reaction occurred. Conclusion Tiotropium bromide was effectiveness and safety in moderate to severe chronic obstructive pulmonary disease.

CHEN Yi, PU Jian-ying. Therapeutic effect of Tiotropium bromide on moderate to severe chronic obstructive pulmonary disease[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(3): 213-215. doi: 10.3969/j.issn.1006-0111.2012.03.015
Citation: CHEN Yi, PU Jian-ying. Therapeutic effect of Tiotropium bromide on moderate to severe chronic obstructive pulmonary disease[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(3): 213-215. doi: 10.3969/j.issn.1006-0111.2012.03.015
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