Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

CHEN Hai-yan. Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 55-57. doi: 10.3969/j.issn.1006-0111.2012.01.015
Citation: CHEN Hai-yan. Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 55-57. doi: 10.3969/j.issn.1006-0111.2012.01.015

Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy

doi: 10.3969/j.issn.1006-0111.2012.01.015
  • Received Date: 2011-12-08
  • Rev Recd Date: 2011-12-18
  • Objective To investigate the effect of combination of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy. Methods 323 patients with diabetic nephropathy were randomly divided into 2 groups. Group I (Compound chuanqiong capsules plus Irbesartan group,n=161)and Group II (Irbesartan group,n=162). After 6 months follow-up,cystatin C,serum creatinine,24 h urine protein quantitate were respectively detected and compared before and after treatment. Results Compared to patients in the control group cystatin C,the patients'serum creatinine,24 h urine protein quantities decreased (P<0.05). Conclusion The combination of Compound Chuanqiong capsules and irbesartan was more effective than irbesartan alone in the treatment of diabetic nephropathy.
  • [1] 陈灏珠.实用内科学:七册[M].12版.北京:人民卫生出版社,2005:10l5.
    [2] 唐 兰,朱西娥,梁已安,等.磷酸川穹嗪对糖尿病周围血管病变的疗效初探[J].中国糖尿病杂志,1997,5(6):323.
    [3] 张曼华.中药川芎嗪合并消栓灵治疗糖尿病性周围神经病变50例体会[J].山东医药,1995,35(9):32.
    [4] 朱开元.安博维提供全面有效的肾脏保护作用[J].国际心血管病杂志,2007, 4:305.
    [5] 李春君,张秋梅.厄贝沙坦对糖尿病高血压的降压疗效及肾脏保护作用[J].实用糖尿病学,2006,5:41.
    [6] 苏 毅.糖尿病肾病发病机制研究进展[J].中国实用医药,2009,5:231.
    [7] Tu X, Chen X, Xie Y, et al. Anti-inflammatory renoprotective effect of clopidogrel and irbesartan in chronic renal injury[J]. J Am Soc Nephrol. 2008,19(1):77.
    [8] 唐 霓.糖尿病血液流变性改变与微血管病变关系的研究进展[J].微循环学杂志,2007,3:60,.
    [9] Parving HH,Lehnert H,Brochner-Mortensen J,et al. The Effect of Irbesartan on the Development of Diabetic Nephropathy in Patients with Type 2 Diabetes[J]. N Engl J Med,2001,345(12):870.
    [10] 张宏宇.中西医结合治疗早期糖尿病肾病31例I临床观察[J].实用诊断与治疗杂志,2004,18(4):296.
    [11] 杨广智.化瘀固肾散治疗糖尿病早期肾病94例临床观察[J].山西中医,2003,19(6):14.
    [12] 焦 鹏.益气活血化瘀法治疗早期糖尿病肾病40例[J].新中医,2004,33(1I): 34.
    [13] 周 江.川芎有效成分及其药理作用研究概况[J].浙江中医杂志,2007,10: 614.
    [14] 玄 阳.当归的药理作用研究进展分析[J].医学信息,2011,24(5):1938.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(3454) PDF downloads(280) Cited by()

Related
Proportional views

Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy

doi: 10.3969/j.issn.1006-0111.2012.01.015

Abstract: Objective To investigate the effect of combination of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy. Methods 323 patients with diabetic nephropathy were randomly divided into 2 groups. Group I (Compound chuanqiong capsules plus Irbesartan group,n=161)and Group II (Irbesartan group,n=162). After 6 months follow-up,cystatin C,serum creatinine,24 h urine protein quantitate were respectively detected and compared before and after treatment. Results Compared to patients in the control group cystatin C,the patients'serum creatinine,24 h urine protein quantities decreased (P<0.05). Conclusion The combination of Compound Chuanqiong capsules and irbesartan was more effective than irbesartan alone in the treatment of diabetic nephropathy.

CHEN Hai-yan. Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 55-57. doi: 10.3969/j.issn.1006-0111.2012.01.015
Citation: CHEN Hai-yan. Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 55-57. doi: 10.3969/j.issn.1006-0111.2012.01.015
Reference (14)

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return