| [1] | MIAO Z W, HU W J, LI Z Y, et al. Involvement of the secreted protein Metrnl in human diseases[J]. Acta Pharmacol Sin,2020,41(12):1525-1530. doi: 10.1038/s41401-020-00529-9 |
| [2] | 王治, 王淑娜, 徐添颖, 等. 烟酰胺磷酸核糖转移酶基因编辑对人胚胎干细胞生长影响的研究[J]. 药学实践杂志, 2019, 37(3):237-240. doi: 10.3969/j.issn.1006-0111.2019.03.009 |
| [3] | WANG S N, XU T Y, LI W L, et al. Targeting nicotinamide phosphoribosyltransferase as a potential therapeutic strategy to restore adult neurogenesis[J]. CNS Neurosci Ther,2016,22(6):431-439. doi: 10.1111/cns.12539 |
| [4] | 李安, 周小青, 孙阔, 等. 药物分子与靶蛋白相互作用的研究进展[J]. 药学实践杂志, 2019, 37(1):1-4,31. doi: 10.3969/j.issn.1006-0111.2019.01.001 |
| [5] | MASLEN C L, BABCOCK D, REDIG J K, et al. CRELD2: gene mapping, alternate splicing, and comparative genomic identification of the promoter region[J]. Gene,2006,382:111-120. doi: 10.1016/j.gene.2006.06.016 |
| [6] | OH-HASHI K, KOGA H, IKEDA S, et al. Role of an ER stress response element in regulating the bidirectional promoter of the mouse CRELD2 - ALG12 gene pair[J]. BMC Genomics,2010,11:664. doi: 10.1186/1471-2164-11-664 |
| [7] | ORTIZ J A, CASTILLO M, DEL TORO E D, et al. The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits[J]. J Neurochem,2005,95(6):1585-1596. doi: 10.1111/j.1471-4159.2005.03473.x |
| [8] | OH-HASHI K, KOGA H, IKEDA S, et al. CRELD2 is a novel endoplasmic Reticulum stress-inducible gene[J]. Biochem Biophys Res Commun,2009,387(3):504-510. doi: 10.1016/j.bbrc.2009.07.047 |
| [9] | HARTLEY C L, EDWARDS S, MULLAN L, et al. Armet/Manf and Creld2 are components of a specialized ER stress response provoked by the inappropriate formation of disulfide bonds: implications for genetic skeletal diseases[J]. Hum Mol Genet,2013,22(25):5262-5275. doi: 10.1093/hmg/ddt383 |
| [10] | OH-HASHI K, NORISADA J, HIRATA Y, et al. Characterization of the role of MANF in regulating the secretion of CRELD2[J]. Biol Pharm Bull,2015,38(5):722-731. doi: 10.1248/bpb.b14-00825 |
| [11] | ZHANG J Y, WENG Y G, LIU X, et al. Endoplasmic Reticulum (ER) stress-inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells[J]. PLoS One,2013,8(9):e73086. doi: 10.1371/journal.pone.0073086 |
| [12] | NUNDLALL S, RAJPAR M H, BELL P A, et al. An unfolded protein response is the initial cellular response to the expression of mutant matriline-3 in a mouse model of multiple epiphyseal dysplasias[J]. Cell Stress Chaperones,2010,15(6):835-849. doi: 10.1007/s12192-010-0193-y |
| [13] | BOYLE S T, POLTAVETS V, KULAR J, et al. ROCK-mediated selective activation of PERK signaling causes fibroblast reprogramming and tumor progression through a CRELD2-dependent mechanism[J]. Nat Cell Biol,2020,22(7):882-895. doi: 10.1038/s41556-020-0523-y |
| [14] | KERN P, BALZER N R, BLANK N, et al. Creld2 function during unfolded protein response is essential for liver metabolism homeostasis[J]. FASEB J,2021,35(10):e21939. |
| [15] | CHEN M F, CHANG C H, YANG L Y, et al. Synovial fluid interleukin-16, interleukin-18, and CRELD2 as novel biomarkers of prosthetic joint infections[J]. Bone Joint Res,2019,8(4):179-188. doi: 10.1302/2046-3758.84.BJR-2018-0291.R1 |
| [16] | KIM Y, PARK S J, MANSON SR, et al. Elevated urinary CRELD2 is associated with endoplasmic Reticulum stress-mediated kidney disease[J]. JCI Insight,2017,2(23):92896. doi: 10.1172/jci.insight.92896 |
| [17] | CANAVES J M, MORSE A, WEST B. PCR primer selection tool optimized for high-throughput proteomics and structural genomics[J]. BioTechniques,2004,36(6):1040-1042. doi: 10.2144/04366BC01 |
| [18] | ASIM A, AGARWAL S, PANIGRAHI I, et al. CRELD1 gene variants and atrioventricular septal defects in Down syndrome[J]. Gene,2018,641:180-185. doi: 10.1016/j.gene.2017.10.044 |
| [19] | BECKERT V, RASSMANN S, KAYVANJOO AH, et al. Creld1 regulates myocardial development and function[J]. J Mol Cell Cardiol,2021,156:45-56. doi: 10.1016/j.yjmcc.2021.03.008 |
| [20] | CLARK H F, GURNEY A L, ABAYA E, et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment[J]. Genome Res,2003,13(10):2265-2270. doi: 10.1101/gr.1293003 |
| [21] | CLARKE R, RESSOM H W, WANG A T, et al. The properties of high-dimensional data spaces: implications for exploring gene and protein expression data[J]. Nat Rev Cancer,2008,8(1):37-49. doi: 10.1038/nrc2294 |
| [22] | GRIFFIN M, ABU-EL-HAIJA M, ABU-EL-HAIJA M, et al. Simplified and versatile method for isolation of high-quality RNA from the pancreas[J]. Biotechniques,2012,52(5):332-334. doi: 10.2144/0000113862 |
| [23] | AZEVEDO-POULY A C P, ELGAMAL O A, SCHMITTGEN T D. RNA isolation from mouse pancreas: a ribonuclease-rich tissue[J]. J Vis Exp,2014(90):e51779. |