[1] MEYER K, PALMER J W. The polysaccharide of the vitreous humor[J]. J Biol Chem,1934,107(3):629-634. doi:  10.1016/S0021-9258(18)75338-6
[2] KOGAN G, SOLTÉS L, STERN R, et al. Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications[J]. Biotechnol Lett,2007,29(1):17-25.
[3] EVANKO S P, TAMMI M I, TAMMI R H, et al. Hyaluronan-dependent pericellular matrix[J]. Adv Drug Deliv Rev,2007,59(13):1351-1365. doi:  10.1016/j.addr.2007.08.008
[4] LAURENT T C, FRASER J R. Hyaluronan[J]. FASEB J,1992,6(7):2397-2404. doi:  10.1096/fasebj.6.7.1563592
[5] 黄小忠, 管国强. 透明质酸生理功能及其应用研究进展[J]. 畜牧与饲料科学, 2015, 36(1):21-25. doi:  10.3969/j.issn.1672-5190.2015.01.008
[6] 陶国枢. 药物流行病学与药品不良反应监测[J]. 中华老年医学杂志, 2005(12):927-928. doi:  10.3760/j:issn:0254-9026.2005.12.016
[7]

GIRISH K S, KEMPARAJU K. The magic glue hyaluronan and its eraser hyaluronidase: a biological overview[J]. Life Sci,2007,80(21):1921-1943. doi:  10.1016/j.lfs.2007.02.037
[8] 陈超, 孙虹, 和培红, 等. 氟喹诺酮类药物不同品种间的安全性差异[J]. 药物不良反应杂志, 2004, 6(5):289-293. doi:  10.3969/j.issn.1008-5734.2004.05.001
[9] 中华医学会眼科学分会角膜病学组. 干眼临床诊疗专家共识(2013年)[J]. 中华眼科杂志, 2013, 49(1):73-75. doi:  10.3760/cma.j.issn.0412-4081.2013.01.020
[10] 俞惠玲. 0.3%透明质酸钠联合普拉洛芬治疗干眼症的临床观察[J]. 临床医药文献电子杂志, 2019, 6(60):71.
[11] 仲元奎, 梁方. A型肉毒素咬肌定点定位注射联合玻尿酸颏部填充注射微整形术重塑女性颌面部轮廓的美容效果分析[J]. 中外女性健康研究, 2020(13):112-113.
[12]

SCHWARTZ S R, HAMMON K A, GAFNER A, et al. Novel hydrolyzed chicken sternal cartilage extract improves facial epidermis and connective tissue in healthy adult females: a randomized, double-blind, placebo-controlled trial[J]. Altern Ther Health Med,2019,25(5):12-29.
[13]

ESPINOZA L, VINSHTOK Y, MCCREESH J, et al. Kinetic energy-assisted delivery of hyaluronic acid for skin remodeling in middle and lower face[J]. J Cosmet Dermatol,2020,19(9):2277-2281. doi:  10.1111/jocd.13339
[14]

SCHAUSS A, SCHWARTZ S, HAMMON K, et al. The effects of skin aging associated with the use of BioCell collagen: a randomized, double-blind, placebo-controlled clinical trial (P06-122-19)[J]. Curr Dev Nutr, 2019, 3(Supplement_1): DOI:  10.1093/cdn/nzz031.p06-122-19.
[15] 薛紫涵, 芦笛, 李桂珍, 等. 面部韧带根部填充透明质酸改善轻中度面部老化[J]. 中国美容医学, 2019, 28(3):1-4.
[16]

AMIRLAK B, MAHEDIA M, SHAH N. A clinical evaluation of efficacy and safety of hyaluronan sponge with vitamin C versus placebo for scar reduction[J]. Plast Reconstr Surg Glob Open,2016,4(7):e792. doi:  10.1097/GOX.0000000000000734
[17]

GUTOWSKI K A. Hyaluronic acid fillers: science and clinical uses[J]. Clin Plast Surg,2016,43(3):489-496. doi:  10.1016/j.cps.2016.03.016
[18]

XIAO S, WAN Y, ZOU F, et al. Prevention of intrauterine adhesion with auto-crosslinked hyaluronic acid gel: a prospective, randomized, controlled clinical study[J]. Zhonghua Fu Chan Ke Za Zhi,2015,50(1):32-36.
[19]

PATEL T, TEVET O. Effective treatment of acne scars using pneumatic injection of hyaluronic acid[J]. J Drugs Dermatol,2015,14(1):74-76.
[20]

CAI Z X, ZHANG H B, WEI Y, et al. Shear-thinning hyaluronan-based fluid hydrogels to modulate viscoelastic properties of osteoarthritis synovial fluids[J]. Biomater Sci,2019,7(8):3143-3157. doi:  10.1039/C9BM00298G
[21]

ITANO N, SAWAI T, YOSHIDA M, et al. Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties[J]. J Biol Chem,1999,274(35):25085-25092. doi:  10.1074/jbc.274.35.25085
[22]

HERMANS J, BIERMA-ZEINSTRA S M A, BOS P K, et al. The effectiveness of high molecular weight hyaluronic acid for knee osteoarthritis in patients in the working age: a randomised controlled trial[J]. BMC Musculoskelet Disord,2019,20(1):196. doi:  10.1186/s12891-019-2546-8
[23]

IALENTI A, DI ROSA M. Hyaluronic acid modulates acute and chronic inflammation[J]. Agents Actions,1994,43(1-2):44-47. doi:  10.1007/BF02005763
[24] 苑树岩, 付庆鹏, 邓晓强. 透明质酸钠治疗膝骨性关节炎的疗效[J]. 大医生, 2019, 4(2):108-109.
[25]

PARK S H, PARK J Y, JI Y B, et al. An injectable click-crosslinked hyaluronic acid hydrogel modified with a BMP-2 mimetic peptide as a bone tissue engineering scaffold[J]. Acta Biomater,2020,117:108-120. doi:  10.1016/j.actbio.2020.09.013
[26]

YANG J, ZHAO R, FENG Q, et al. Development of a carrier system containing hyaluronic acid and protamine for siRNA delivery in the treatment of melanoma[J]. Invest New Drugs,2021,39(1):66-76. doi:  10.1007/s10637-020-00986-3
[27]

ZHANG Y, LIU Q, YANG N, et al. Hyaluronic acid and oxidized regenerated cellulose prevent adhesion reformation after adhesiolysis in rat models[J]. Drug Des Devel Ther,2016,10:3501-3507. doi:  10.2147/DDDT.S103824
[28] 蔡同凯, 韩华, 曹永兵, 等. 医用透明质酸钠凝胶的防粘连作用及对伤口愈合、抗生素作用的影响[J]. 药学服务与研究, 2020, 20(2):92-97.
[29]

LEE J W, PARK J Y, PARK S H, et al. Cross-linked electrospun cartilage acellular matrix/poly(caprolactone-co-lactide-co-glycolide) nanofiber as an antiadhesive barrier[J]. Acta Biomater,2018,74:192-206. doi:  10.1016/j.actbio.2018.05.032
[30]

PAŞCALĂU V, TERTIS M, PALL E, et al. Bovine serum albumin gel/polyelectrolyte complex of hyaluronic acid and chitosan based microcarriers for Sorafenib targeted delivery[J]. J Appl Polym Sci,2020,137(34):49002. doi:  10.1002/app.49002
[31]

MANSOORI B, MOHAMMADI A, ABEDI-GABALLU F, et al. Hyaluronic acid-decorated liposomal nanoparticles for targeted delivery of 5-fluorouracil into HT-29 colorectal cancer cells[J]. J Cell Physiol,2020,235(10):6817-6830. doi:  10.1002/jcp.29576
[32] 杨桂兰, 郭学平, 栾贻宏. 不同相对分子质量透明质酸钠的应用[J]. 食品与药品, 2005, 7(12):1-3. doi:  10.3969/j.issn.1672-979X.2005.12.001
[33]

LEE H, MOK H, LEE S, et al. Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels[J]. J Control Release,2007,119(2):245-252. doi:  10.1016/j.jconrel.2007.02.011
[34]

LEE H, LEE K, PARK T G. Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity[J]. Bioconjugate Chem,2008,19(6):1319-1325. doi:  10.1021/bc8000485
[35]

BAJAJ G, KIM M R, MOHAMMED S I, et al. Hyaluronic acid-based hydrogel for regional delivery of paclitaxel to intraperitoneal tumors[J]. J Control Release,2012,158(3):386-392. doi:  10.1016/j.jconrel.2011.12.001
[36]

LIU X, LIU H, WANG S L, et al. Hyaluronic acid derivative-modified nano-structured lipid carrier for cancer targeting and therapy[J]. J Zhejiang Univ Sci B,2020,21(7):571-580. doi:  10.1631/jzus.B1900624
[37]

CHOI K Y, JEON E J, YOON H Y, et al. Theranostic nanoparticles based on PEGylated hyaluronic acid for the diagnosis, therapy and monitoring of colon cancer[J]. Biomaterials,2012,33(26):6186-6193. doi:  10.1016/j.biomaterials.2012.05.029
[38]

ZHANG Z, SUNER S S, BLAKE D A, et al. Antimicrobial activity and biocompatibility of slow-release hyaluronic acid-antibiotic conjugated particles[J]. Int J Pharm,2020,576:119024. doi:  10.1016/j.ijpharm.2020.119024
[39]

STERN R, JEDRZEJAS M J. Hyaluronidases: their genomics, structures, and mechanisms of action[J]. Chem Rev,2006,106(3):818-839. doi:  10.1021/cr050247k
[40]

COSTAGLIOLA C, DEL PRETE A, WINKLER N R, et al. The ability of bacteria to use Na-hyaluronate as a nutrient[J]. Acta Ophthalmol Scand,1996,74(6):566-568.
[41]

ZHANG M, MCDONALD F M, STURROCK S S, et al. Group A Streptococcus cell-associated pathogenic proteins as revealed by growth in hyaluronic acid-enriched media[J]. Proteomics,2007,7(9):1379-1390. doi:  10.1002/pmic.200600578
[42]

PIRNAZAR P, WOLINSKY L, NACHNANI S, et al. Bacteriostatic effects of hyaluronic acid[J]. J Periodontol,1999,70(4):370-374. doi:  10.1902/jop.1999.70.4.370
[43]

CARLSON G A, DRAGOO J L, SAMIMI B, et al. Bacteriostatic properties of biomatrices against common orthopaedic pathogens[J]. Biochem Biophys Res Commun,2004,321(2):472-478. doi:  10.1016/j.bbrc.2004.06.165
[44]

LEE J H, LIU A R, PARK J H, et al. Therapeutic effects of hyaluronic acid in peritonitis-induced Sepsis in mice[J]. Shock,2020,54(4):488-497. doi:  10.1097/SHK.0000000000001512
[45]

THEOCHARIS A D, VYNIOS D H, PAPAGEORGAKOPOULOU N, et al. Altered content composition and structure of glycosaminoglycans and proteoglycans in gastric carcinoma[J]. Int J Biochem Cell Biol,2003,35(3):376-390. doi:  10.1016/S1357-2725(02)00264-9
[46]

GARCÍA I, VIZOSO F, SUÁREZ C, et al. Relationship of tumoral hyaluronic acid and cathepsin D contents with histological type of gastric carcinoma[J]. Int J Biol Markers,2000,15(3):215-218. doi:  10.1177/172460080001500302
[47]

LLANEZA A, VIZOSO F, RODRÍGUEZ J C, et al. Hyaluronic acid as prognostic marker in resectable colorectal cancer[J]. Br J Surg,2000,87(12):1690-1696.
[48]

SUGAHARA K N, MURAI T, NISHINAKAMURA H, et al. Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells[J]. J Biol Chem,2003,278(34):32259-32265. doi:  10.1074/jbc.M300347200
[49]

SIMPSON M A, WILSON C M, MCCARTHY J B. Inhibition of prostate tumor cell hyaluronan synthesis impairs subcutaneous growth and vascularization in immunocompromised mice[J]. Am J Pathol,2002,161(3):849-857. doi:  10.1016/S0002-9440(10)64245-9
[50]

ITANO N, SAWAI T, ATSUMI F, et al. Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation[J]. J Biol Chem,2004,279(18):18679-18687. doi:  10.1074/jbc.M313178200
[51]

TOOLE B P. Hyaluronan in morphogenesis[J]. Semin Cell Dev Biol,2001,12(2):79-87. doi:  10.1006/scdb.2000.0244
[52]

BHARADWAJ A G, RECTOR K, SIMPSON M A. Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis[J]. J Biol Chem,2007,282(28):20561-20572. doi:  10.1074/jbc.M702964200
[53]

TAMMI R H, KULTTI A, KOSMA V M, et al. Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan[J]. Semin Cancer Biol,2008,18(4):288-295. doi:  10.1016/j.semcancer.2008.03.005
[54] 黄岳山, 潘艺茗, 薛静. 不同相对分子量透明质酸功能及应用的研究[J]. 透析与人工器官, 2010, 21(4):22-25.
[55] 郭群英, 叶任高, 黄文生, 等. 不同分子量透明质酸对人腹膜间皮细胞透明质酸合成酶mRNA表达的影响[J]. 中国中西医结合肾病杂志, 2002, 3(6):320-322,331. doi:  10.3969/j.issn.1009-587X.2002.06.003
[56]

BERDIAKI A, NIKITOVIC D, TSATSAKIS A, et al. bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells[J]. Biochim Biophys Acta,2009,1790(10):1258-1265. doi:  10.1016/j.bbagen.2009.06.013
[57] 蔡同凯, 杨文胜, 曹永兵, 等. 医用透明质酸钠凝胶对肿瘤生长和转移影响的实验研究[J]. 药学实践杂志, 2020, 38(2):129-134.
[58]

GHATAK S, MISRA S, TOOLE B P. Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway[J]. J Biol Chem,2002,277(41):38013-38020. doi:  10.1074/jbc.M202404200
[59]

HALL C L, LANGE L A, PROBER D A, et al. pp60(c-src) is required for cell locomotion regulated by the hyaluronanreceptor RHAMM[J]. Oncogene,1996,13(10):2213-2224.