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微凝胶的制备及其在药物缓控释系统中的应用

李佩瑶,  黄月英,  李传灵,  卞俊

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文章导航 > 药学实践与服务  > 2019 >  37(3): 212-215,221
李佩瑶, 黄月英, 李传灵, 卞俊. 微凝胶的制备及其在药物缓控释系统中的应用[J]. 药学实践与服务, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
引用本文: 李佩瑶, 黄月英, 李传灵, 卞俊. 微凝胶的制备及其在药物缓控释系统中的应用[J]. 药学实践与服务, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
shu
LI Peiyao, HUANG Yueying, LI Chuanling, BIAN Jun. Preparation and application of micro gels in sustained and controlled release drug delivery systems[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
Citation: LI Peiyao, HUANG Yueying, LI Chuanling, BIAN Jun. Preparation and application of micro gels in sustained and controlled release drug delivery systems[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
shu

微凝胶的制备及其在药物缓控释系统中的应用

doi: 10.3969/j.issn.1006-0111.2019.03.004
  • 1.

    海军军医大学附属长海医院虹口院区药学科, 上海 200434;江西中医药大学, 江西 南昌 330004

  • 2.

    海军军医大学附属长海医院虹口院区药学科, 上海 200434

基金项目: 海军军医大学军事课题（2017JS11）

Preparation and application of micro gels in sustained and controlled release drug delivery systems

  • 1.

    Department of Pharmacy, Hongkou Branch, Changhai Hospital Affiliated to Naval Medical University, Shanghai 200434, China;Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China

  • 2.

    Department of Pharmacy, Hongkou Branch, Changhai Hospital Affiliated to Naval Medical University, Shanghai 200434, China

  • 摘要: 微凝胶是一种具有分子内交联网状结构，粒径在0.1~100 μm之间的功能性聚合物，具有粒径小、载药量高、环境响应性灵敏、生物相容性好等特点，在药物缓控释系统中的应用具有独特优势。笔者在查阅近年国内外文献的基础上综述了微凝胶的基本特性、制备方法、制备材料及在药物缓控释系统中的应用。
    Abstract: Micro gels are functional polymer with intramolecular crosslinked network structure and particle size between 0.1 and 100 μm.Micro gels have the characteristics of small particle size,high drug loading,and good environmental responsiveness and biocompatibility,which has unique advantages in the application of drug controlled release systems.A brief introduction in characteristics,preparation methods,preparation materials and applications of micro gels in drug controlled release systems was given in this review.
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微凝胶的制备及其在药物缓控释系统中的应用

doi: 10.3969/j.issn.1006-0111.2019.03.004
  • 1. 海军军医大学附属长海医院虹口院区药学科, 上海 200434;江西中医药大学, 江西 南昌 330004
  • 2. 海军军医大学附属长海医院虹口院区药学科, 上海 200434
    • 基金项目:  海军军医大学军事课题（2017JS11）
  • 收稿日期: 2018-08-14
  • 修回日期: 2018-10-15

摘要: 微凝胶是一种具有分子内交联网状结构，粒径在0.1~100 μm之间的功能性聚合物，具有粒径小、载药量高、环境响应性灵敏、生物相容性好等特点，在药物缓控释系统中的应用具有独特优势。笔者在查阅近年国内外文献的基础上综述了微凝胶的基本特性、制备方法、制备材料及在药物缓控释系统中的应用。

English Abstract

李佩瑶, 黄月英, 李传灵, 卞俊. 微凝胶的制备及其在药物缓控释系统中的应用[J]. 药学实践与服务, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
引用本文: 李佩瑶, 黄月英, 李传灵, 卞俊. 微凝胶的制备及其在药物缓控释系统中的应用[J]. 药学实践与服务, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
shu
LI Peiyao, HUANG Yueying, LI Chuanling, BIAN Jun. Preparation and application of micro gels in sustained and controlled release drug delivery systems[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
Citation: LI Peiyao, HUANG Yueying, LI Chuanling, BIAN Jun. Preparation and application of micro gels in sustained and controlled release drug delivery systems[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(3): 212-215,221. doi: 10.3969/j.issn.1006-0111.2019.03.004
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