Clinical pharmacists in promoting the rational use of angiotensin-converting enzyme inhibitors in the CCU
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摘要: 目的 提高血管紧张素转换酶抑制剂（ACEI）的使用合理性。 方法 临床药师查阅2012年5月—2013年5月本院冠心病监护病区（CCU）所有病例，参照ACEI专家共识、指南以及药品说明书的标准对ACEI的使用合理性进行分析，但不予任何干预。2013年6月—2015年5月，临床药师参照同样标准，对ACEI的使用合理性进行干预。 结果 对比干预前后的数据发现，ACEI使用百分比从80.1%提高至98.9%，ACEI起始剂量偏大的百分比由21.4%下降至0.9%，ACEI剂量不足的百分比从4.7%降至0.5%，差异均有统计学意义。 结论 临床药师在促进ACEI的使用合理性方面可起主导作用。
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关键词:
- 血管紧张素转换酶抑制剂 /
- 合理性 /
- 临床药师
Abstract: Objective To improve the rational use of angiotensin-converting enzyme inhibitors (ACEI). Methods Clinical pharmacists reviewed ACEI use for the patients admitted into coronary heart disease care unit (CCU) during May 2012 to May 2013 to analyze the rational use of ACEI according to the expert consensus standards, guidelines and drug instructions of ACEI without any interventions. Clinical pharmacists intervened the irrational use of ACEI based on the same standard from June 2013 to May 2015. Results By comparing the data before and after intervention, it was found that the percentage of ACEI use increased from 80.1% to 98.9%. The percentage of initial ACEI overdose was dropped from 21.4% to 0.9%, and the percentage of under dose was decreased from 4.7% to 0.5%, which was statistically significant. Conclusion Clinical pharmacists can play a leading role in promoting the rational use of ACEI. -
[1] 陈盛新,栾智鹏. 药物治疗与病人保健［J］. 药学实践杂志,2009,27(1):73-77. [2] 中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 慢性收缩性心力衰竭治疗建议［J］. 中华心血管病杂志,2002,30(1):7-23. [3] 中华医学会心血管病学分会, 中华心血管病杂志编辑委员会, 中国循环杂志编辑委员会. 急性心肌梗死诊断和治疗指南［J］. 中华心血管病杂志,2001,29(12):710-725. [4] Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report［J］. JAMA,2003,289(19):2560-2572. [5] Cheng J, Zhang W, Zhang X,et al. Effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality, cardiovascular deaths, and cardiovascular events in patients with diabetes mellitus: a meta-analysis［J］.JAMA Intern Med, 2014,174(5):773-85. [6] Sandra SA, Elizabeth L, Lopez C. Intervention to improve adherence to ACC/AHA recommended adjunctive medications for the management of patients with an acute myocardial infarction［J］. Clin Cardiol, 2001,24:114-118. [7] 中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 血管紧张素转化酶抑制剂在心血管病中应用中国专家共识［J］. 中华心血管杂志,2007,35(2):97-106. [8] 翟晓波,朱 珺. 智能化和精确化用药监测软件的研发及应用［J］. 中国现代应用药学. 2010,27(4):361-366. [9] 张晓荧,张四喜,周 微,等. 肾内科临床药师在药物整合服务中的实践探索［J］. 药学实践杂志,2015,33(1):88-90. -
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