The research and establishment of antibiotics differentiated indexes for clinical application in Department of Digestive System
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摘要: 目的 制订本院消化内科常见疾病抗菌药物临床应用规范，确立该科抗菌药物临床应用差异化指标，从而促进消化内科常见疾病抗菌药物的合理使用。 方法 回顾性抽取本院消化内科2014年全年所有住院患者共2 060例，按疾病比例从中随机抽取300份病例。根据相关治疗指南及法律法规，制订该科常见疾病的抗菌药物临床应用规范；通过分析和统计，确定该科住院患者抗菌药物使用率、使用强度，最终制订抗菌药物临床应用差异化指标。 结果 该科住院患者理论抗菌药物使用率、使用强度分别为29.0%、41.5 DDDs，实际抗菌药物使用率、使用强度分别为40.3%、50.3 DDDs。 结论 制订该科抗菌药物临床应用差异化指标，对提高抗菌药物临床应用水平有重要意义。Abstract: Objective To promote the rational antibacterial drug use for common digestive system (DS) diseases by reviewing the clinical application of antibacterial drugs for hospitalized patients, formulating the hospital clinical specification of antibacterial drugs for common DS diseases and establishing the clinical application of antibacterial drug differentiation index for DS department. Methods 300 cases were selected from 2 060 hospitalized DS patients in the year 2014 based on the given disease ratio. The usage rate and intensity of antibiotics were calculated with survey and medical statistical analysis. The differentiation index for the clinical application of antibacterial drugs were established. Results Theoretical values of usage rate and use intensity of antibiotics in DS department were 29.0%, 41.5 DDDs according to analysis. However, the practical values were 40.3%, 50.3 DDDs. Conclusion It is necessary to improve the level of clinical antibacterial drug use. One effective way to achieve such goal is to establish the differentiation index of antibacterial drug clinical application for the department.
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