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来源于天然产物的抗肿瘤先导结构研究进展

武善超,  盛春泉,  张万年

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武善超, 盛春泉, 张万年. 来源于天然产物的抗肿瘤先导结构研究进展[J]. 药学实践与服务, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
引用本文: 武善超, 盛春泉, 张万年. 来源于天然产物的抗肿瘤先导结构研究进展[J]. 药学实践与服务, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
shu
WU Shanchao, SHENG Chunquan, ZHANG Wannian. Advance in anti-cancer lead-compounds derived from natural products[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
Citation: WU Shanchao, SHENG Chunquan, ZHANG Wannian. Advance in anti-cancer lead-compounds derived from natural products[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
shu

来源于天然产物的抗肿瘤先导结构研究进展

doi: 10.3969/j.issn.1006-0111.2014.05.005

  • 第二军医大学药学院, 上海 200433

基金项目: 国家自然科学基金重点项目(30930107).

Advance in anti-cancer lead-compounds derived from natural products

  • School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • 摘要: 肿瘤严重威胁人类生命健康,因此发现新结构类型、新作用机制、更有效的抗肿瘤药成为当务之急。天然产物在抗肿瘤药物发现过程中有着重要的作用和意义。综述几种具有抗肿瘤活性的天然产物,重点阐述其作用机制、抗肿瘤活性及构效关系的研究进展。
    Abstract: Cancer is a serious threat to human life and health. Therefore, there is an emergent need to develop novel anti-cancer agents with new structural type, new mechanism of action and higher efficacy. Natural products had played a key role in the discovery of anticancer agents. The anti-cancer activity, mechanism of action, structure and activity relationship of several lead-compounds which were derived from natural products were summarized in this review.
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  • 收稿日期:  2013-03-11
  • 修回日期:  2013-06-25

来源于天然产物的抗肿瘤先导结构研究进展

doi: 10.3969/j.issn.1006-0111.2014.05.005
  • 第二军医大学药学院, 上海 200433
    • 基金项目:  国家自然科学基金重点项目(30930107).
  • 收稿日期: 2013-03-11
  • 修回日期: 2013-06-25

摘要: 肿瘤严重威胁人类生命健康,因此发现新结构类型、新作用机制、更有效的抗肿瘤药成为当务之急。天然产物在抗肿瘤药物发现过程中有着重要的作用和意义。综述几种具有抗肿瘤活性的天然产物,重点阐述其作用机制、抗肿瘤活性及构效关系的研究进展。

English Abstract

武善超, 盛春泉, 张万年. 来源于天然产物的抗肿瘤先导结构研究进展[J]. 药学实践与服务, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
引用本文: 武善超, 盛春泉, 张万年. 来源于天然产物的抗肿瘤先导结构研究进展[J]. 药学实践与服务, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
shu
WU Shanchao, SHENG Chunquan, ZHANG Wannian. Advance in anti-cancer lead-compounds derived from natural products[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
Citation: WU Shanchao, SHENG Chunquan, ZHANG Wannian. Advance in anti-cancer lead-compounds derived from natural products[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(5): 337-341,371. doi: 10.3969/j.issn.1006-0111.2014.05.005
shu

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