留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码
x 关闭 永久关闭

应中央军委要求，2022年9月起，《药学实践杂志》将更名为《药学实践与服务》，双月刊，正文96页；2023年1月起，拟出版月刊，正文64页，数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿！

聚乙烯醇衍生物作为水凝胶材料的应用研究进展

胡晓,  胡容峰,  白中稳

downloadPDF
文章导航 > 药学实践与服务  > 2013 >  31(3): 169-172,180
胡晓, 胡容峰, 白中稳. 聚乙烯醇衍生物作为水凝胶材料的应用研究进展[J]. 药学实践与服务, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
引用本文: 胡晓, 胡容峰, 白中稳. 聚乙烯醇衍生物作为水凝胶材料的应用研究进展[J]. 药学实践与服务, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
shu
HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
Citation: HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
shu

聚乙烯醇衍生物作为水凝胶材料的应用研究进展

doi: 10.3969/j.issn.1006-0111.2013.03.002

  • 安徽中医学院, 安徽 合肥 230031

Applied research of polyvinyl alcohol derivatives as hydrogel materials

  • Anhui University of Traditional Chinese Medicine, Hefei 230031, China

  • 摘要: 目的 介绍PVA衍生物作为水凝胶材料的应用研究进展,为进一步开发它提供依据和参考。 方法 参阅近年来国内外相关文献资料,对其进行综合、分析和归纳。 结果 PVA水凝胶具有亲水性、柔软性、温和性和良好的生物相容性,其衍生物作为普通水凝胶和智能水凝胶材料被广泛应用于生物医药学领域。 结论 PVA是一种极具再次开发潜力的优良药用辅料,具有很大的应用价值。
    Abstract: Objective To introduce the application research progress of PVA derivatives as hydrogel materials, and provide the basis and reference for further development. Methods The related documents at home and abroad in recent years were integrated, analyzed and summarized. Results PVA derivatives as conventional and sensitive hydrogel materials were widely used in the fields of biomedicine, having a hydrophilic, softness, mild characteristics and good biocompatibility. Conclusion PVA is an excellent pharmaceutical excipient for potential re-development, and having a great value.
  • [1] Sailaja GS,Sreenivasan K,Yokogawa Y,et al.Bioinspired mineralization andcell adhesion on surface functionalized PVA films[J].Acta Biomater,2009,5(5):1647.
    [2] Singh B,Sharma V.Design of psyllium-PVA-acrylic acid based novel hydrogels for use in antibiotic drug delivery[J].Int J Pharm,2010,389:94.
    [3] AL-Sabagh AM, Abdeen Z. Preparation and characterization of hydrogel based on PVA cross-linked by different cross-linkers used to dry organic solvents[J]. J Polym Environ,2010,18:576.
    [4] Otsuka E, Sugiyama M, Suzuki A. Formation and destruction of physical crosslinks by mild treatments in chemically crosslinked PVA gels[J].Polym Bull,2010,10:1007.
    [5] Wang JQ, Satoh M. Water properties in a novel thermoswelling PVA derivative hydrogel as studied by NMR and FTIR[J]. Langmuir, 2010, 26(16):13607.
    [6] Padavan DT,Hamilton AM,Millon LE,et al.Synthesis, characterization and in vitro cell compatibility study of a PAA graft/cross-linked PVA hydrogel[J]. ActaBiomaterialia,2011,7:258.
    [7] Alves MH,Young CJ,Bozzetto K,et al.Degradable,click PVA hydrogels:characterization of degradation and cellular compatibility[J]. Biomed Mater,2011,7:1.
    [8] Artyukhov AA,Shtilman MI,Kuskov AN,et al.Macroporous polymeric hydrogels formed from acrylate modified PVA macromers[J].Eur Polym J,2011,10(18):667.
    [9] Pan YS,Xiong DS,Gao F.Viscoelastic behavior of no-HA reinforced PVA gel biocomposites as an articular cartilage[J].J Mater Sci,2008,19:1963.
    [10] Cho SH,Lim SM,Han DK,et al.Time-dependent alginate/PVA hydrogels as injectable cell carriers[J].JBiomat Sci-Polym E,2009,20:863.
    [11] Negishi J,Nam KW,Kimura TS,et al.High-hydrostatic pressure technique is an effective method for the preparation of PVA-heparin hybridgel[J].Eur J Pharm Sci,2010,41:617.
    [12] Zan XJ,Kozlov M,McCarthy TJ,et al.Covalently attached, silver-doped PVA hydrogel films on Poly(L-lactic acid)[J].Biomacromolecules,2010,11:1082.
    [13] Abitbol T,Johnstone T,Quinn TM,et al.Reinforcement with cellulose nanocrystals of PVA hydrogels prepared by cyclic freezing and thawing[J].Soft Matter,2011,7:2373.
    [14] Bakhshandeh H,Soleimani M,Hosseini SS,et al.Poly (ε-caprolactone) nanofibrous ring surrounding a PVA hydrogel for the development of a biocompatible two-part artificial cornea[J].Int J Nanomed,2011,6:1509.
    [15] Sukhanova TV,Artyukhov AA,Prudchenko IA,et al.Entrapment and in vitro release of delta-sleep inducing peptide from polymer hydrogels based on modified PVA[J]. Biomedical Chemistry, 2012, 6(2):149.
    [16] 姚女兆.果胶/PVA复合水凝胶人工髓核的实验研究[D].南方医科大学,2010.
    [17] Aboutaleb MF,Ismail SA,El-kelesh NA.Radiation synthesis and characterization of PVA/MAA-GEL hydrogel for vitro drug delivery[J].J Macromol Sci B,2009,46:170.
    [18] Wang B,Liu MZ,Chen ZB,et al.Preparation, characterization and controlled release investigation of interpenetrating polymer networks of PAA/triazole modified PVA[J].Int J Pharm,2007,331:19.
    [19] 祝宝东,孟静,王鉴,等. PVA/淀粉接枝P(AA-AM)互穿网络水凝胶的合成与性能研究[J].科学技术与工程, 2011, 11(10):2234.
    [20] Qi BW,Yu AX,Zhu SB,et al.The preparation and cytocompatibility of injectable thermosensitive CS/PVA hydrogel[J].Med Sci,2010,30(1):89.
    [21] Tang YF,Du YM,Li Y,et al.A thermosensitive CS/PVA hydrogel containing hydroxyapatite for protein delivery[J].J Biomed Mater Res A, 2009, 91(4):953.
    [22] 陈丽如. CS/PVA温敏性水凝胶给药系统的研究[D].河北大学,2011.
    [23] 史林峰.PVA/AM接枝共聚物水凝胶的制备及表征[J].中国组织工程研究,2012,16(21):3919.
    [24] Zhang NY,Shen YG,Li XQ,et al.Synthesis and characterization of thermoand pH-sensitive PVA/poly(N,N-diethylacrylamide-co-itaconic acid) semi-IPN hydrogels[J].Biomed Mater,2012,7:1.
  • [1] 陈炳辰, 佟达丰, 万苗, 闫飞虎, 姚建忠.  UPLC-MS/MS法测定小鼠血浆中紫杉醇脂肪酸酯前药及其药代动力学研究 . 药学实践与服务, 2024, 42(): 1-5. doi: 10.12206/j.issn.2097-2024.202404082
    [2] 王耀振, 徐灿, 吕顺莉, 田泾, 张东炜.  钾离子竞争性酸阻滞剂的药学特征研究进展 . 药学实践与服务, 2024, 42(7): 1-7. doi: 10.12206/j.issn.2097-2024.202306040
    [3] 马兹芬, 许维恒, 金煜翔, 薛磊.  食管癌的靶向治疗与免疫治疗研究进展 . 药学实践与服务, 2024, 42(6): 231-237. doi: 10.12206/j.issn.2097-2024.202306008
    [4] 徐飞, 陈瑾, 鲁育含, 李志勇.  肠道菌群参与糖尿病肾病的机制研究进展 . 药学实践与服务, 2024, 42(5): 181-184, 197. doi: 10.12206/j.issn.2097-2024.202312023
    [5] 张林晨, 张小琴, 张俊平.  山楂酸药理作用的研究进展 . 药学实践与服务, 2024, 42(5): 185-189. doi: 10.12206/j.issn.2097-2024.202307052
    [6] 丁千雪, 尚圣兰, 余梦辰, 余爱荣.  机器学习在肾病综合征患者他克莫司个体化用药中的应用 . 药学实践与服务, 2024, 42(6): 227-230, 243. doi: 10.12206/j.issn.2097-2024.202310007
    [7] 景凯, 杨慈荣, 张圳, 臧艺蓓, 刘霞.  黄芪甲苷衍生物治疗慢性心力衰竭小鼠的药效评价及作用机制研究 . 药学实践与服务, 2024, 42(5): 190-197. doi: 10.12206/j.issn.2097-2024.202310004
  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  2572
  • HTML全文浏览量:  247
  • PDF下载量:  143
  • 被引次数: 0
出版历程
  • 收稿日期:  2012-09-17
  • 修回日期:  2013-01-25

聚乙烯醇衍生物作为水凝胶材料的应用研究进展

doi: 10.3969/j.issn.1006-0111.2013.03.002
  • 安徽中医学院, 安徽 合肥 230031
  • 收稿日期: 2012-09-17
  • 修回日期: 2013-01-25

摘要: 目的 介绍PVA衍生物作为水凝胶材料的应用研究进展,为进一步开发它提供依据和参考。 方法 参阅近年来国内外相关文献资料,对其进行综合、分析和归纳。 结果 PVA水凝胶具有亲水性、柔软性、温和性和良好的生物相容性,其衍生物作为普通水凝胶和智能水凝胶材料被广泛应用于生物医药学领域。 结论 PVA是一种极具再次开发潜力的优良药用辅料,具有很大的应用价值。

English Abstract

胡晓, 胡容峰, 白中稳. 聚乙烯醇衍生物作为水凝胶材料的应用研究进展[J]. 药学实践与服务, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
引用本文: 胡晓, 胡容峰, 白中稳. 聚乙烯醇衍生物作为水凝胶材料的应用研究进展[J]. 药学实践与服务, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
shu
HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
Citation: HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
shu

    全文HTML

参考文献 (24)

目录

    /

    返回文章
    返回

    版权所有：《药学实践与服务》编辑委员会

    主管、主办: 中国人民解放军海军军医大学地址: 上海市杨浦区国和路325号邮政编码: 200433

    电话: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    本系统由 北京仁和汇智信息技术有限公司 开发    百度统计