The practice of spectrum analysis experiment teaching based on comprehensive structure identification
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摘要: 以综合解析为导向的光谱分析实验教学,旨在通过对未知化合物紫外光谱、红外光谱、核磁共振波谱及质谱数据的采集与分析,模拟新药研发过程中采用四大光谱确定未知化合物结构的流程,加深学生对光谱法基本理论知识的理解,训练学生规范操作光谱分析仪器,促进学生形成光谱综合解析的基本思路,提高学生的实践能力。Abstract: The practice of spectrum analysis experiment teaching based on comprehensive structure identification was to simulate the procedure of elucidating structure by spectroscopy methods, including UV, IR, NMR and MS in new drug research, which could help students to understand the theory of spectrum analysis, get standard instrument operating practice and form the basic thought of comprehensive structure identification with improving practical ability.
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[1] 李发美. 分析化学[M].北京:人民卫生出版社,2011:4. [2] 杨云, 李银环, 慕慧. 深化分析化学实验教学改革培养学生的实验创新能力[J]. 西北医学教育,2010,18(5):987. [3] 余鹏, 牟玲丽. 药学专业仪器分析实验教学改革的探讨[J]. 中国医药导报,2011,8(8):104. -
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