Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy
-
摘要: 目的 统计分析肝切除术后患者SIRS的水平及动态变化,为临床进一步降低肝切除患者的感染率提供帮助。 方法 调查我院单个治疗组近4年来收治的肝切除患者发生的SIRS情况,并进行回顾性分析。 结果 232例肝切除患者中发生SIRS的有226例,总发生率为96.98%;随着术后天数的延长, SIRS发生的严重程度呈逐步下降趋势;原发性肝癌组术后SIRS达峰值与肿瘤最大径、肝硬化相关;SIRS评分与选择双联或者三联抗菌药物之间并不存在可比性。 结论 我院单个治疗组肝切除术后患者SIRS的发生率高,应用SIRS评分重视早期发现SIRS,对提高肝切除的治愈率,降低感染率,具有一定的临床意义。Abstract: Objective To analyze the lever and dynamics of systemic inflammatory response syndrome in the patients after hepatectomy, so as to provide some references for the treatment of preventing SIRS and decrease of infection rate. Methods The occurrence of SIRS on patients of hepatectomy in single treatment group nearly 4 years were surveyed byretrospective analysis. Results The rate of SIRS was 96.98% in the 232 cases of hepatectomy. SIRS severity occurred gradually declined with the extension of treatment after surgery. The SIRS Peak after surgery was correlated with maximum tumor diameter and cirrhosis of liver on primary liver cancer group. There was no comparability between the SIRS Score and antibiotics combined with double or triple. Conclusions The application of SIRS Score and early detection of SIRS was a certain clinical significance to improve the cure rate of liver resection and reduce infection rates.
-
Key words:
- hepatectomy /
- systemic inflammatory response syndrome /
- incidence /
- influencing factor
-
[1] 吴孟超,陈汉,姚晓平,等.原发性肝癌的外科治疗[J].中华外科杂志,1996,46(12):47. [2] Cavaillon JM,Annane D.Compartmentalization of the inflammatory response in sepsis and SIRS[J].J Endotoxin Res,2006,12(3):151. [3] Bone RC, Balk RA, Cerra FB,et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The American College of Chest Physicians Society of Critioal Care Medicine comsensus Conference[J].Chest,1992,101(6):1644. [4] Wittmann DH,Schein M,Condon RE.Management of secondary peritonitis[J].Ann Surg,1996,224(1):10. [5] 陈自平,卢圣爱,徐昌青,等.重型病毒性肝炎患者医院感染及其预防[J]. 中华医院感染学杂志,2005,15(7):790. -
点击查看大图
计量
- 文章访问数: 2662
- HTML全文浏览量: 164
- PDF下载量: 207
- 被引次数: 0
下载:
