复方参蛇洗剂的研制和评价
Preparation and evaluation of compound Shenshe lotion
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摘要: 目的 研究复方参蛇洗剂的制备方法。 方法 采用正交设计法优化复方参蛇洗剂的制备方法,建立了制剂的质量评价方法,观察复方参蛇洗剂的抗炎、抑菌、止痒等与药效学相关的药理作用。 结果 研制的复方参蛇洗剂工艺稳定,质量可靠,具有明显的抗炎、抑菌、止痒作用。 结论 研制的复方参蛇洗剂具有一定的临床应用前景。Abstract: Objective To study the preparation method of compound Shenshe lotion. Methods The preparation method was optimized by orthogonal design and the determination method was constructed. The pharmacological effects of compound Shenshe lotion including the anti-inflammation, bacteriostasis and anti-pruritus were studied. Results The preparation and quality control methods were stable and reliable. The compound Shenshe lotion had apparent effects of anti-inflammatory, anti-bacterial and anti-pruritic. Conclusions The compound Shenshe lotion was feasible for the clinical application.
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Key words:
- compound /
- Lightyellow Sophora Root /
- Fructus Cnidii /
- lotion
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[1] 中国药典2010年版.二部[S].2010:461. [2] 张 杰,向大雄,罗杰英.等.反相高效液相色谱法测定苦参药材中苦参碱的含量[J].中国医院药学杂志,2004,24(11):718. [3] 刘 斌,石任兵,周素蓉.苦参汤有效部位总生物碱含量测定方法研究[J].北京中医药大学学报 2004,27(2):76. [4] 江苏新医学院. 中药大辞典[M]. 上海:上海科学技术出版社. 1975:2121. -
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