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木质素次生代谢工程的研究概况和进展

胡永胜,  肖莹,  邸鹏,  张磊,  陈万生

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文章导航 > 药学实践与服务  > 2011 >  29(4): 256-259,271
胡永胜, 肖莹, 邸鹏, 张磊, 陈万生. 木质素次生代谢工程的研究概况和进展[J]. 药学实践与服务, 2011, 29(4): 256-259,271.
引用本文: 胡永胜, 肖莹, 邸鹏, 张磊, 陈万生. 木质素次生代谢工程的研究概况和进展[J]. 药学实践与服务, 2011, 29(4): 256-259,271.
shu
HU Yong-sheng, XIAO Ying, DI Peng, ZHANG Lei, CHEN Wan-sheng. Advances of metabolic engineering in lignin biosynthesis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 256-259,271.
Citation: HU Yong-sheng, XIAO Ying, DI Peng, ZHANG Lei, CHEN Wan-sheng. Advances of metabolic engineering in lignin biosynthesis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 256-259,271.
shu

木质素次生代谢工程的研究概况和进展

  • 1.

    第二军医大学长征医院药学部,上海 20003;解放军第118医院药械科,浙江 温州 325000

  • 2.

    第二军医大学长征医院药学部,上海 20003;第二军医大学现代中药研究中心,上海 200433

  • 3.

    第二军医大学生药学教研室,上海 200433

Advances of metabolic engineering in lignin biosynthesis

  • 1.

    Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;Department of Pharmacy, The 118th Hospital of PLA,Wenzhou 325000,China

  • 2.

    Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;Modern Research Center for Traditional Chinese Medicine, Second Military Medical University, Shanghai 200433,China

  • 3.

    Department of Pharmacognosy,School of Pharmacy,Second Military Medical University,Shanghai 200433,China

  • 摘要: 目的 介绍木质素次生代谢工程的研究概况和进展。 方法 通过查阅文献,对木质素结构、生源合成、系统生物学和调控新策略等方面的进展作一综述。 结果和结论 木质素是酚类多聚体,是维管植物细胞壁的重要组成成分。木质素单体的次生代谢途径已经被阐明,木质素单体的种类及比例可以被基因工程手段调控。
    Abstract: Objective To introduce advances of metabolic engineering in lignin biosynthesis. Methods The structure of lignin, biosynthesis, systems biology and new metabolic engineering strategies were reviewed. Results & Conclusions Lignin was a phenolic polymer, which was usually located in the secondary walls of plant cells. Secondary metabolic pathways of lignin monomers had been stated, and the types and proportions of lignin monomer could be regulated by metabolic engineering.
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    [2] Ralph J, Lundquist K, Brunow G, et al. Lignins: natural polymers from oxidative coupling of 4-hydroxyphenyl-propanoids[J]. Phytochemistry Reviews, 2004, 3(1): 29.
    [3] Guo D, Chen F, Inoue K, et al. Downregulation of caffeic acid 3-O-methyltransferase and caffeoyl CoA 3-O-methyltransferase in transgenic alfalfa: impacts on lignin structure and implications for the biosynthesis of G and S lignin[J]. The Plant Cell Online, 2001, 13(1): 73.
    [4] Bayindir U, Alfermann AW, Fuss E. Hinokinin biosynthesis in Linum corymbulosum Reichenb[J]. Plant J, 2008, 55(5): 810.
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    [24] Rohde A, Morreel K, Ralph J, et al. Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism[J]. Plant Cell, 2004, 16(10): 2749.
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  • 收稿日期:  2010-06-07
  • 修回日期:  2010-12-14

木质素次生代谢工程的研究概况和进展

  • 1. 第二军医大学长征医院药学部,上海 20003;解放军第118医院药械科,浙江 温州 325000
  • 2. 第二军医大学长征医院药学部,上海 20003;第二军医大学现代中药研究中心,上海 200433
  • 3. 第二军医大学生药学教研室,上海 200433
  • 收稿日期: 2010-06-07
  • 修回日期: 2010-12-14

摘要: 目的 介绍木质素次生代谢工程的研究概况和进展。 方法 通过查阅文献,对木质素结构、生源合成、系统生物学和调控新策略等方面的进展作一综述。 结果和结论 木质素是酚类多聚体,是维管植物细胞壁的重要组成成分。木质素单体的次生代谢途径已经被阐明,木质素单体的种类及比例可以被基因工程手段调控。

English Abstract

胡永胜, 肖莹, 邸鹏, 张磊, 陈万生. 木质素次生代谢工程的研究概况和进展[J]. 药学实践与服务, 2011, 29(4): 256-259,271.
引用本文: 胡永胜, 肖莹, 邸鹏, 张磊, 陈万生. 木质素次生代谢工程的研究概况和进展[J]. 药学实践与服务, 2011, 29(4): 256-259,271.
shu
HU Yong-sheng, XIAO Ying, DI Peng, ZHANG Lei, CHEN Wan-sheng. Advances of metabolic engineering in lignin biosynthesis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 256-259,271.
Citation: HU Yong-sheng, XIAO Ying, DI Peng, ZHANG Lei, CHEN Wan-sheng. Advances of metabolic engineering in lignin biosynthesis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 256-259,271.
shu

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