复方氧氟沙星滴鼻液的制备及应用
Preparation and clinical applieation of compound ofloxacin nasal drop
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摘要: 本文拟定了复方氧氟沙星滴鼻液处方制备工艺和质量控制标准,并对其进行了稳定性试验。采用紫外分光光度法测定了氧氟沙里的吸收度,盐酸麻黄碱在波长293nm处无干扰。结果表明该制剂应用安全.疗效可靠.室温放置12mo质量仍符合要求。Abstract: We studied the method of preparation and quality control of compound ofloxacin nasal drop.The determination of ofloxacin and ephedrine hydrochloride in nasal drops was established by ultraviolet spectropho-tometry at the wavelength 293nm and by acid-alkalic titration,The stability of compound ofloxacin nasal drops were tested.The therapetic results showed the reliable curative effect and safety.
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Key words:
- Ofloxacin /
- ephedrine hydrochloride /
- nasal drop
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