氮酮对葛根素透皮吸收作用的实验研究
Effect of azone on the transdermal absorption of puerarin liniment
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摘要: 本实验采用简单小室法。以离体仔猪皮为透皮屏障,以生理盐水为接受液,研究了不同浓度的氮酮对葛根素透皮吸收作用的影响。实验结果表明,经皮吸收12h,含氮酮1%、2%、3%各个组之间,以及与不含氮酮的对照组之间,其透皮吸收率在统计学上有极显着差异(P<0.01)。Abstract: The transdermal absorption of puerarin liniment containing 1%,2%,3%of azone,and without azone was studied by isolated pigline skin in vitro. It was demonstrated the liniment containing azone could increase the skin penetration in 12 hours.
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Key words:
- azone /
- puerarin /
- transdermal absorption
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