[1] KELLY J R, BORRE Y, O' BRIEN C, et al. Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat[J]. J Psychiatr Res,2016,82:109-118. doi:  10.1016/j.jpsychires.2016.07.019
[2] 查伟, 李树生, 徐柯, 等. 柴桂温胆定志汤联合帕罗西汀治疗抑郁症疗效和安全性评价[J]. 中国药业, 2019, 28(13):53-55. doi:  10.3969/j.issn.1006-4931.2019.13.016
[3] GILBERT K, ARSENEAULT-BRÉARD J, FLORES MONACO F, et al. Attenuation of post-myocardial infarction depression in rats by n-3 fatty acids or probiotics starting after the onset of reperfusion[J]. Br J Nutr,2013,109(1):50-56. doi:  10.1017/S0007114512003807
[4] ZHUANG F, ZHOU X, GAO X, et al. Cytokines and glucocorticoid receptors are associated with the antidepressant-like effect of alarin[J]. Peptides,2016,76:115-129. doi:  10.1016/j.peptides.2016.01.002
[5] 汪崇泽, 盛国红. 免疫炎症途径与抑郁症的研究进展[J]. 精神医学杂志, 2015, 28(5):397-400. doi:  10.3969/j.issn.2095-9346.2015.05.025
[6] AAN HET ROT M, MATHEW S J, CHARNEY D S. Neurobiological mechanisms in major depressive disorder[J]. CMAJ,2009,180(3):305-313. doi:  10.1503/cmaj.080697
[7] HAMON M, BLIER P. Monoamine neurocircuitry in depression and strategies for new treatments[J]. Prog Neuropsychopharmacol Biol Psychiatry,2013,45:54-63. doi:  10.1016/j.pnpbp.2013.04.009
[8] PYTKA K, DZIUBINA A, MŁYNIEC K, et al. The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect[J]. Pharmacol Rep,2016,68(2):443-450. doi:  10.1016/j.pharep.2015.10.006
[9] MORAITIS A G, BLOCK T, NGUYEN D, et al. The role of glucocorticoid receptors in metabolic syndrome and psychiatric illness[J]. J Steroid Biochem Mol Biol, 2017, 165(pt a): 114-120.
[10] LIU Y X, ZHANG L, WANG X Q, et al. Similar fecal microbiota signatures in patients with diarrhea-predominant irritable bowel syndrome and patients with depression[J]. Clinical Gastroenterology and Hepatology,2016,14(11):1602-1611.e5. doi:  10.1016/j.cgh.2016.05.033
[11] CHEN Z, LI J, GUI S, et al. Comparative metaproteomics analysis shows altered fecal microbiota signatures in patients with major depressive disorder[J]. Neuroreport,2018,29(5):417-425. doi:  10.1097/WNR.0000000000000985
[12] YU M, JIA H, ZHOU C, et al. Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics[J]. J Pharm Biomed Anal,2017,138:231-239. doi:  10.1016/j.jpba.2017.02.008
[13] 刘佳琳. 肠道菌群介导的栀子豉汤抗抑郁作用及配伍机制研究[D]. 上海: 海军军医大学, 2019.
[14] JIANG H, LING Z, LING Z, et al. Altered fecal microbiota composition in patients with major depressive disorder[J]. Brain Behav Immun,2015,48:186-194. doi:  10.1016/j.bbi.2015.03.016
[15] RONG HAN. A case-control study on the abundance, species and gene functional pathway of gut microbiota in patients with depression[J]. China Med Abstr Intern Med,2017,34(3):191-192.
[16] MESSAOUDI M, LALONDE R, VIOLLE N, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects[J]. Br J Nutr,2011,105(5):755-764. doi:  10.1017/S0007114510004319
[17] VAN DE WOUW M, BOEHME M, LYTE J M, et al. Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations[J]. J Physiol,2018,596(20):4923-4944. doi:  10.1113/JP276431
[18] CHEN J J, ZHOU C J, LIU Z, et al. Divergent urinary metabolic phenotypes between major depressive disorder and bipolar disorder identified by a combined GC–MS and NMR spectroscopic metabonomic approach[J]. J Proteome Res,2015,14(8):3382-3389. doi:  10.1021/acs.jproteome.5b00434
[19] CORRÊA-OLIVEIRA R, FACHI J L, VIEIRA A, et al. Regulation of immune cell function by short-chain fatty acids[J]. Clin Trans Immunol,2016,5(4):e73. doi:  10.1038/cti.2016.17
[20] SCHROEDER F A, LIN C L, CRUSIO W E, et al. Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse[J]. Biological psychiatry,2007,62(1):55-64. doi:  10.1016/j.biopsych.2006.06.036
[21] YAMAWAKI Y, YOSHIOKA N, NOZAKI K, et al. Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice[J]. Brain Res,2018,1680:13-38. doi:  10.1016/j.brainres.2017.12.004
[22] NANKOVA B B, AGARWAL R, MACFABE D F, et al. Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells - possible relevance to autism spectrum disorders[J]. PLoS One,2014,9(8):e103740. doi:  10.1371/journal.pone.0103740
[23] VAN DER VEEN F M, EVERS E A, DEUTZ N E, et al. Effects of acute tryptophan depletion on mood and facial emotion perception related brain activation and performance in healthy women with and without a family history of depression[J]. Neuropsychopharmacology,2007,32(1):216-224. doi:  10.1038/sj.npp.1301212
[24] CLARKE G, GRENHAM S, SCULLY P, et al. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner[J]. Mol Psychiatry,2013,18(6):666-673. doi:  10.1038/mp.2012.77
[25] BHATTACHARYA S K, MITRA S K, ACHARYA S B. Anxiogenic activity of isatin, a putative biological factor, in rodents[J]. J Psychopharmacol,1991,5(3):202-206. doi:  10.1177/026988119100500304
[26] RÍOS-COVIÁN D, RUAS-MADIEDO P, MARGOLLES A, et al. Intestinal short chain fatty acids and their link with diet and human health[J]. Front Microbiol,2016,7:185.
[27] LAURITZEN K H, MORLAND C, PUCHADES M, et al. Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism[J]. Cerebral Cortex,2014,24(10):2784-2795. doi:  10.1093/cercor/bht136
[28] RUSSELL D W. The enzymes, regulation, and genetics of bile acid synthesis[J]. Annu Rev Biochem,2003,72(1):137-174. doi:  10.1146/annurev.biochem.72.121801.161712
[29] QUINN M, MCMILLIN M, GALINDO C, et al. Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms[J]. Dig Liver Dis,2014,46(6):527-534. doi:  10.1016/j.dld.2014.01.159
[30] RAIMONDI F, SANTORO P, BARONE M V, et al. Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation[J]. Am J Physiol-Gastrointest Liver Physiol,2008,294(4):G906-G913. doi:  10.1152/ajpgi.00043.2007
[31] MOORE L B, GOODWIN B, JONES S A, et al. St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor[J]. PNAS,2000,97(13):7500-7502. doi:  10.1073/pnas.130155097
[32] 安邦, 张大维, 赵珊珊, 等. 双歧杆菌三联活菌辅助帕罗西汀治疗女性抑郁症患者效果观察及机制探讨[J]. 山东医药, 2020, 60(29):58-60. doi:  10.3969/j.issn.1002-266X.2020.29.016
[33] 吴国琳, 余国友, 范小芬, 等. 单味中药及其有效成份对肠道微生态的调节作用研究概况[J]. 中国中医药现代远程教育, 2015, 13(9):134-136. doi:  10.3969/j.issn.1672-2779.2015.09.067