[1] FORCINA G C, DIXON S J. GPX4 at the crossroads of lipid homeostasis and ferroptosis[J]. Proteomics, 2019, 19(18):e1800311. doi:  10.1002/pmic.201800311
[2] XIE Y C, KANG R, KLIONSKY D J, et al. GPX4 in cell death, autophagy, and disease[J]. Autophagy, 2023, 19(10):2621-2638. doi:  10.1080/15548627.2023.2218764
[3] GALLUZZI L, VITALE I, AARONSON S A, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018[J]. Cell Death Differ, 2018, 25(3):486-541. doi:  10.1038/s41418-017-0012-4
[4] ZHAO Y C, LI Y Q, ZHANG R F, et al. The role of erastin in ferroptosis and its prospects in cancer therapy[J]. Onco Targets Ther, 2020, 13:5429-5441. doi:  10.2147/OTT.S254995
[5] SCHEERER P, BORCHERT A, KRAUSS N, et al. Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4(GPx4)[J]. Biochemistry, 2007, 46(31):9041-9049. doi:  10.1021/bi700840d
[6] SAVASKAN N E, UFER C, KÜHN H, et al. Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function[J]. Biol Chem, 2007, 388(10):1007-1017. doi:  10.1515/BC.2007.126
[7] YANG W S, STOCKWELL B R. Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells[J]. Chem Biol, 2008, 15(3):234-245. doi:  10.1016/j.chembiol.2008.02.010
[8] YANG W S, SRIRAMARATNAM R, WELSCH M E, et al. Regulation of ferroptotic cancer cell death by GPX4[J]. Cell, 2014, 156(1-2):317-331. doi:  10.1016/j.cell.2013.12.010
[9] LIU H, FOROUHAR F, LIN A J, et al. Small-molecule allosteric inhibitors of GPX4[J]. Cell Chemical Biology, 2022, 29(12):1680-93. doi:  10.1016/j.chembiol.2022.11.003
[10] WEÏWER M, BITTKER J A, LEWIS T A, et al. Development of small-molecule probes that selectively kill cells induced to express mutant RAS[J]. Bioorg Med Chem Lett, 2012, 22(4):1822-1826. doi:  10.1016/j.bmcl.2011.09.047
[11] CHEN T T, LENG J F, TAN J, et al. Discovery of novel potent covalent glutathione peroxidase 4 inhibitors as highly selective ferroptosis inducers for the treatment of triple-negative breast cancer[J]. J Med Chem, 2023, 66(14):10036-10059. doi:  10.1021/acs.jmedchem.3c00967
[12] XU C J, XIAO Z H, WANG J, et al. Discovery of a potent glutathione peroxidase 4 inhibitor as a selective ferroptosis inducer[J]. J Med Chem, 2021, 64(18):13312-13326. doi:  10.1021/acs.jmedchem.1c00569
[13] EATON J K, RUBERTO R A, KRAMM A, et al. Diacylfuroxans are masked nitrile oxides that inhibit GPX4 covalently[J]. J Am Chem Soc, 2019, 141(51):20407-20415. doi:  10.1021/jacs.9b10769
[14] EATON J K, FURST L, RUBERTO R A, et al. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles[J]. Nat Chem Biol, 2020, 16(5):497-506. doi:  10.1038/s41589-020-0501-5
[15] SHIMADA K, SKOUTA R, KAPLAN A, et al. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis[J]. Nat Chem Biol, 2016, 12(7):497-503. doi:  10.1038/nchembio.2079
[16] GASCHLER M M, ANDIA A A, LIU H R, et al. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation[J]. Nat Chem Biol, 2018, 14(5):507-515. doi:  10.1038/s41589-018-0031-6