[1] PARSONS C G. CNS repurposing-potential new uses for old drugs: Examples of screens for Alzheimer's disease, Parkinson's disease and spasticity[J]. Neuropharmacology,2019,147:4-10. doi:  10.1016/j.neuropharm.2018.08.027
[2] LIU Y X, WU W, LIANG Y J, et al. New uses for old drugs: the tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China[J]. Molecules,2014,19(9):15058. doi:  10.3390/molecules190915058
[3] CHEN V C, CHAN H L, HSU T C, et al. New use for old drugs: The protective effect of atypical antipsychotics on hepatocellular carcinoma[J]. Int J Cancer,2019,144(10):2428-2439. doi:  10.1002/ijc.31980
[4] YEOMANS N D. Aspirin: old drug, new uses and challenges[J]. J Gastroenterol Hepatol,2011,26(3):426-431. doi:  10.1111/j.1440-1746.2010.06569.x
[5] PATRONO C. Aspirin: new cardiovascular uses for an old drug[J]. Am J Med,2001,110(1A):62S-65S.
[6] YANG B W, SHI J L. Developing new cancer nanomedicines by repurposing old drugs[J]. Angew Chem Int Ed Engl,2020,59(49):21829-21838. doi:  10.1002/anie.202004317
[7] NELSON B S, KREMER D M, LYSSIOTIS C A. New tricks for an old drug[J]. Nat Chem Biol,2018,14(11):990-991. doi:  10.1038/s41589-018-0137-x
[8] 赵方振, 庄春林, 郭子照, 等. 1H-吡咯-2(5H)-酮类化合物的合成及生物活性[J]. 药学实践杂志, 2012, 30(6):430-432, 456.
[9] LI J, WU Y L, GUO Z Z, et al. Discovery of 1-arylpyrrolidone derivatives as potent p53-MDM2 inhibitors based on molecule fusing strategy[J]. Bioorg Med Chem Lett,2014,24(12):2648-2650. doi:  10.1016/j.bmcl.2014.04.063
[10] MIAO Z Y, ZHU L J, DONG G Q, et al. A new strategy to improve the metabolic stability of lactone: discovery of (20S, 21S)-21-fluorocamptothecins as novel, hydrolytically stable topoisomerase I inhibitors[J]. J Med Chem,2013,56(20):7902-7910. doi:  10.1021/jm400906z
[11] ZHUANG C L, MIAO Z Y, ZHU L J, et al. Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53-MDM2 protein-protein interaction[J]. J Med Chem,2012,55(22):9630-9642. doi:  10.1021/jm300969t
[12] WARNER W A, SANCHEZ R, DAWOODIAN A, et al. Identification of FDA-approved drugs that computationally bind to MDM2[J]. Chem Biol Drug Des,2012,80(4):631-637. doi:  10.1111/j.1747-0285.2012.01428.x