滚轮微针处理次数对药物皮肤渗透、分布及皮肤刺激性的影响

张娟娟; 傅翔; 朱全刚; 张立超; 张娟娟; 傅翔; 朱全刚; 张立超

doi:10.3969/j.issn.1006-0111.2019.05.006

[1]

占浩慧,黄颖聪,马凤森.微针穿刺性能评价方法研究进展[J].中国药学杂志,2018,53(22):1890-1895.

[2]

李雅,张娟娟,张立超,等.改装滚轮微针促进人增生性瘢痕皮肤对醋酸曲安奈德的吸收[J].第二军医大学学报,2015,36(1):58-64.

[3]

张娟娟,张立超,朱全刚,等.改装滚轮微针用于醋酸曲安奈德经皮给药的特性试验[J].中国医院药学杂志,2015,35(4):292-296.

[4]

ZHOUC P,LIU Y L,WANG H L,et al.Transdermal delivery of insulin using microneedle rollers in vivo[J].Int J Pharm,2010,392(1-2):127-133.

[5]

YOONJ,PARK D,SON T,et al.A physical method to enhance transdermal delivery of a tissue optical clearing agent:combination of microneedling and sonophoresis[J].Lasers Surg Med,2010,42(5):412-417.

[6]

BADRAN M M,KUNTSCHE J,FAHR A.Skin penetration enhancement by a microneedle device (Dermaroller) in vitro:dependency on needle size and applied formulation[J].Eur J Pharm Sci,2009,36(4-5):511-523.

[7]

YOUS K,NOH Y W,PARK H H,et al.Effect of applying modes of the polymer microneedle-roller on the permeation of L-ascorbic acid in rats[J].J Drug Target,2010,18(1):15-20.

[8]

张娟娟,朱全刚,张立超,等.不同密度滚轮微针对维A酸经皮渗透的影响[J].药学服务与研究,2013,13(6):440-444.

[9]

张娟娟.力度可控性滚轮微针的构建及其对大面积皮肤药物吸收影响研究[D].宁夏:宁夏医科大学,2014.

[10]

鞠强.维A酸类药物在痤疮治疗中的应用[J].皮肤病与性病,2018,40(1):26-28.

[11]

WANG Q,JAIMES-LIZCANO Y A,LAWSON L B,et al.Improved dermal delivery of FITC-BSA using a combination of passive and active methods[J].J Pharm Sci,2011,100(11):4804-4814.