[1] Williams JP, Brown SL, Georges GE, et al. Animal models for medical countermeasures to radiation exposure[J]. Radiat Res, 2010,173(4):557-578.
[2] Hauer-Jensen M, Denham JW, Andreyev HJ. Radiation enteropathy- -pathogenesis, treatment and prevention[J]. Nat Rev Gastroenterol Hepatol, 2014,11(8):470-479.
[3] Theis VS, Sripadam R, Ramani V, et al. Chronic radiation enteritis[J]. Clin Oncol (R Coll Radiol), 2010,22(1):70-83.
[4] Singh VK, Newman VL, Berg AN, et al. Animal models for acute radiation syndrome drug discovery[J]. Expert Opin Drug Discov, 2015,10(5):497-517.
[5] Houchen CW, Stenson WF, Cohn SM. Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury[J]. Am J Physiol Gastrointest Liver Physiol, 2000,279(5):G858-865.
[6] Ciorba MA, Riehl TE, Rao MS, et al. Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner[J]. Gut, 2012,61(6):829-838.
[7] Vance DE, Vance JE. Biochemistry of lipids, lipoproteins and membranes[M]. 5th ed. San Diego:Elsevier, 2008:332-361.
[8] Smith WL, Song I. The enzymology of prostaglandin endoperoxide H synthases-1 and -2[J]. Prostaglandins Other Lipid Mediat, 2002,(68-69):115-128.
[9] Jackson LM, Wu KC, Mahida YR, et al. Cyclooxygenase (COX) 1 and 2 in normal, inflamed, and ulcerated human gastric mucosa[J]. Gut, 2000,47(6):762-770.
[10] Zhang Z, Andoh A, Inatomi O, et al. Interleukin-17 and lipopolysaccharides synergistically induce cyclooxygenase-2 expression in human intestinal myofibroblasts[J]. J Gastroenterol Hepatol, 2005,20(4):619-627.
[11] Brown SL, Riehl TE, Walker MR, et al. Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury[J]. J Clin Invest, 2007,117(1):258-269.
[12] Hall E J. Radiobiology for the radiologist[M]. 5th ed. USA:Lippincott Williams & Wilkins, 2000:32-66.
[13] Shadad AK, Sullivan FJ, Martin JD, et al. Gastrointestinal radiation injury:symptoms, risk factors and mechanisms[J]. World J Gastroenterol, 2013,19(2):185-198.
[14] Barker N. Adult intestinal stem cells:critical drivers of epithelial homeostasis and regeneration[J]. Nat Rev Mol Cell Biol, 2014,15(1):19-33.
[15] Riehl T, Cohn S, Tessner T, et al. Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism[J]. Gastroenterology, 2000,118(6):1106-1016.
[16] Walker MR, Brown SL, Riehl TE, et al. Growth factor regulation of prostaglandin-endoperoxide synthase 2(Ptgs2) expression in colonic mesenchymal stem cells[J]. J Biol Chem, 2010,285(7):5026-5039.
[17] Zhang X, Schwarz EM, Young DA, et al. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair[J]. J Clin Invest, 2002,109(11):1405-1415.
[18] Kurtova AV, Xiao J, Mo Q, et al. Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance[J]. Nature, 2015,517(7533):209-213.
[19] Houchen CW, Sturmoski MA, Anant S, et al. Prosurvival and antiapoptotic effects of PGE2 in radiation injury are mediated by EP2 receptor in intestine[J]. Am J Physiol Gastrointest Liver Physiol, 2003,284(3):G490-498.