[1] Brown GD,Denning DW,Levitz SM.Tackling human fungal infections[J].Science,2012,336(6082):647.
[2] Lai CC,Tan CK,Huang YT,et al.Current challenges in the management of invasive fungal infections[J].J Infect Chemother,2008,14(2):77.
[3] Park BJ,Wannemuehler KA,Marston BJ,et al.Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS[J].AIDS. 2009, 23(4):525.
[4] Sheng C,Zhang W.New lead structures in antifungal drug discovery[J].Curr Med Chem.2011,18(5): 733.
[5] Liu J,Balasubramanian MK.1,3-beta-Glucan synthase:a useful target for antifungal drugs[J].Curr Drug Targets Infect Disord.2001,1(2):159.
[6] Kondoh O, Inagaki Y, Fukuda H,et al.Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase[J].Biol Pharm Bull, 2005,28(11):2138.
[7] Ting PC,Kuang R,Wu H,et al.The synthesis and structure-activity relationship of pyridazinones as glucan synthase inhibitors[J].Bioorg Med Chem Lett.2011,21(6):1819.
[8] Zhou G,Ting PC,Aslanian R,et al.SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors[J].Bioorg Med Chem Lett.2011,21(10):2890.
[9] Guinea J,Recio S,Escribano P,et al.In vitro antifungal activities of isavuconazole and comparators against rare yeast pathogens[J].Antimicrob Agents Chemother.2010,54(9):4012.
[10] Miller JL,Schell WA,Wills EA,et al.In vitro and in vivo efficacies of the new triazole albaconazole against Cryptococcus neoformans[J].Antimicrob Agents Chemother,2004,48(2):384.
[11] Sheng C,Zhang W,Zhang M,et al.Homology modeling of lanosterol 14-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate interactions[J].J Biomol Struct & Dyn,2004,22(1):91.
[12] Sheng C,Wang W,Che X,et al.Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization[J].Chem Med Chem,2010,5(3):390.
[13] Sheng C,Miao Z,Ji H,et al.Three-dimensional model of lanosterol 14 alpha-demethylase from Cryptococcus neoformans: active-site characterization and insights into azole binding[J].Antimicrob Agents Chemother,2009,53(8):3487.
[14] Sheng C,Che X,Wang W,et al.Design and synthesis of novel triazole antifungal derivatives by structure-based bioisosterism[J].Eur J Med Chem,2011,46(11):5276.
[15] Sheng C,Che X,Wang W,et al.Structure-based design,synthesis,and antifungal activity of new triazole derivatives[J].Chem Biol Drug Des,2011,78(2):309.
[16] Wang W,Wang S,Liu Y,et al.Novel conformationally restricted triazole derivatives with potent antifungal activity[J].Eur J Med Chem. 2010,45(2):6020.
[17] Sun N,Wen J,Lu G,et al.An ultra-fast LC method for the determination of iodiconazole in microdialysis samples and its application in the calibration of laboratory-made linear probes[J].J Pharm Biomed Anal,2010,51(1):248.
[18] Weston SA,Camble R,Colls J,et al.Crystal structure of the anti-fungal target N-myristoyl transferase[J].Nat Struct Biol,1998,5(3):213.
[19] Sogabe S,Masubuchi M,Sakata K,et al.Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors[J].Chem Biol,2002,9(10):1119.
[20] Farazi TA,Waksman G,Gordon JJ. The biology and enzymology of protein N-myristoyla[J].J Biol Chem,2001,276(43):39051.
[21] Yamazaki K,Kaneko Y,Suwa K,et al.Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure[J].J Biol Chem,2005,13(7):2509.
[22] Ebara S,Naito H,Nakazawa K,et al.FTR1335 is a novel synthetic inhibitor of Candida albicans N-myristoyltransferase with fungicidal activity[J].Biol Pharm Bull,2005,28(4):591.
[23] Sheng C,Zhu J,Zhang W,et al.3D-QSAR and molecular docking studies on benzothiazole derivatives as Candida albicans N-myristoyltransferase inhibitors[J].Eur J Med Chem,2007,42(4):477.
[24] Sheng C,Xu H,Wang W,et al.Design, synthesis and antifungal activity of isosteric analogues of benzoheterocyclic N-myristoyltransferase Inhibitors[J].Eur J Med Chem,2010,45(9):3531.
[25] 盛春泉,张万年,王文雅,等. 取代四氢咔唑类抗真菌化合物及其制备方法[P].中国专利,201110094585.4,2011-04-15.
[26] Cutfield SM,Dodson EJ,Anderson BF,et al.The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors[J].Structure,1995,3(11):1261.
[27] Stewart K,Abad-Zapatero C.Candida proteases and their inhibition: prospects for antifungal therapy[J].Curr Med Chem,2001,8(8):941.[JP2]
[28] Degel B,Staib P,Rohrer S,et al.Cis-Configured aziridines are new pseudo-irreversible dual-mode inhibitors of Candida albicans secreted aspartic protease 2[J].Chem Med Chem 2008,3(2):302.
[29] Trabocchi A,Mannino C,Machetti F,et al.Identification of inhibitors of drug-resistant Candida albicans strains from a library of bicyclic peptidomimetic compounds[J].J Med Chem,2010,53(6):2502.